Electron Imaging Center for NanoMachines

EICN provides advanced electron imaging tools for applications ranging from materials science to structural biology 

Electron Imaging Center for Nanomachines

Publications

Users of the EICN Laboratory are requested to acknowledge their use of the Technology Centers at CNSI in their scholarly publications. All publications listed here included data acquired or generated in the EICN Laboratory.

  • Al Mamun, A. A., Wu, C., Chang, C., Sanchez, B. C., Das, A., & Ton-That, H. (2022). A cell wall-anchored glycoprotein confers resistance to cation stress in Actinomyces oris biofilms. Molecular Oral Microbiology. 2022, Mar 15; 37(5): 206–217. doi: 10.1111/omi.12365.
  • Bowler, J. T., Sawaya, M. R., Boyer, D. R., Cascio, D., Bali, M., & Eisenberg, D. S. (2022). Micro-electron diffraction structure of the aggregation-driving n terminus of drosophila neuronal protein orb2a reveals amyloid-like β-sheets. Journal of Biological Chemistry. 2022, Aug 18; 298(10): 102396. doi: 10.1016/j.jbc.2022.102396.
  • He, Y., Song, H., Chan, H., Liu, B., Wang, Y., Sušac, L., Zhou, Z. H., & Feigon, J. (2022). Structure of tetrahymena telomerase-bound CST with polymerase α-primase. Nature. 2022, Jul 13; 608(7924): 813–818. doi: 10.1038/s41586-022-04931-7.
  • Huang, J., Sementa, L., Liu, Z., Barcaro, G., Feng, M., Liu, E., Jiao, L., Xu, M., Leshchev, D., Lee, S.-J., Li, M., Wan, C., Zhu, E., Liu, Y., Peng, B., Duan, X., Goddard, W. A., Fortunelli, A., Jia, Q., & Huang, Y. (2022). Experimental Sabatier plot for predictive design of active and stable PT-alloy oxygen reduction reaction catalysts. Nature Catalysis. 2022, Jun 9; 5(6): 513–523. doi: 10.1038/s41929-022-00797-0.
  • Jiang, Y. X., Cao, Q., Sawaya, M. R., Abskharon, R., Ge, P., DeTure, M., Dickson, D. W., Fu, J. Y., Ogorzalek Loo, R. R., Loo, J. A., &Eisenberg, D. S. (2022). Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43. Nature. 2022, Mar 28; 605 (7909): 304–309. doi: 10.1038/s41586-022-04670-9.
  • Jiang, Y. X., Cao, Q., Sawaya, M. R., Abskharon, R., Ge, P., DeTure, M., Dickson, D. W., Fu, J. Y., Ogorzalek Loo, R. R., Loo, J. A., & Eisenberg, D. S. (2022). Amyloid fibrils in frontotemporal lobar degeneration with TDP-43 inclusions are composed of TMEM106B, rather than TDP-43. bioRxiv. 2022, Feb 1. doi:10.1101/2022.01.31.478523.
  • Jin Huang, Bosi Peng, Thomas Stracensky, Zeyan Liu, Ao Zhang, Mingjie Xu, Yang Liu, Zipeng Zhao, Xiangfeng Duan, Qingying Jia, & Yu Huang. 1D PtCo nanowires as catalysts for PEMFCs with low Pt loading. China Mater. 65, 704–711 (2022). https://doi.org/10.1007/s40843-021-1777-x
  • Liu, B., He, Y., Wang, Y., Song, H., Zhou, Z. H., & Feigon, J. (2022). Structure of active human telomerase with telomere shelterin protein TPP1. Nature. 2022, Apr 13; 604(7906): 578–583. doi: 10.1038/s41586-022-04582-8.
  • Qi Qian, Huaying Ren, Jingyuan Zhou, Zhong Wan, Jingxuan Zhou, Xingxu Yan, Jin Cai, Peiqi Wang, Bailing Li, Zdenek Sofer, Bo Li, Xidong Duan, Xiaoqing Pan, Yu Huang, Xiangfeng Duan. Chiral molecular intercalation superlattices. Nature 606, 902–908 (2022). https://doi.org/10.1038/s41586-022-04846-3
  • Seidler, P. M., Murray, K. A., Boyer, D. R., Ge, P., Sawaya, M. R., Hu, C. J., Cheng, X., Abskharon, R., Pan, H., DeTure, M. A., Williams, C. K., Dickson, D. W., Vinters, H. V., & Eisenberg, D. S. (2022). Structure-based discovery of small molecules that disaggregate alzheimer’s disease tissue derived tau fibrils in vitro. Nature Communications. 2022, Sep 16; 13(1): 1-12. doi: 10.1038/s41467-022-32951-4.
  • Si, Z., Zhou, K., Tsao, J., Luo, M., & Zhou, Z. H. (2022). Locations and in situ structure of the polymerase complex inside the virion of vesicular stomatitis virus. Proceedings of the National Academy of Sciences.2022, Jul 2; 119(18): e2111948119. doi: 10.1073/pnas.2111948119
  • Tetreau, G., Sawaya, M. R., De Zitter, E., Andreeva, E. A., Banneville, A.-S., Schibrowsky, N. A., Coquelle, N., Brewster, A. S., Grünbein, M. L., Kovacs, G. N., Hunter, M. S., Kloos, M., Sierra, R. G., Schiro, G., Qiao, P., Stricker, M., Bideshi, D., Young, I. D., Rodriguez, J., … Colletier, J. P. (2022). De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals. Nature Communications. 2022, Jul 28; 13(1): 4376. doi: 10.1038/s41467-022-31746-x.
  • Yang, Y., Liu, S., Egloff, S., Eichhorn, C. D., Hadjian, T., Zhen, J., Kiss, T., Zhou, Z. H., & Feigon, J. (2022). Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP. Molecular Cell. 2022, May 5; 82(9): 1724-1736. doi: 10.1016/j.molcel.2022.03.001.
  • Zhekova, H. R., Wang, W., Tsirulnikov, K., Kayık, G., Khan, H. M., Azimov, R., Abuladze, N., Kao, L., Newman, D., Noskov, S., Tieleman, D. P.,Zhou, Z. H., Pushkin, A., & Kurtz, I. (2022). Insights Into the Na+-Dependent Anion Exchange in the SLC4 Family From the Cryo-EM Structure of the Sodium-Driven Chloride/Bicarbonate Exchanger SLC4A8. The FASEB Journal. 2022, May 13; 36(S1). doi: 10.1096/fasebj.2022.36.s1.r2784.
  • Cai, X., Liu, L., Qiu, C., Wen, C., He, Y., Cui, Y., Li, S., Zhang, X., Zhang, L., Tian, C., Bi, L., Zhou, Z. H., & Gong, W. (2021). Identification and architecture of a putative secretion tube across mycobacterial outer envelope. Science Advances. 2021, Aug 20; 7(34): eabg5656. doi: 10.1126/sciadv.abg5656.
  • He, Y., Song, H., Chan, H., Wang, Y., Liu, B., Susac, L., Zhou, Z. H., & Feigon, J.(2021). Structure of telomerase-bound CST with polymerase α-primase. bioRxiv. 2021, Dec 28. doi: 10.1101/2021.12.28.474374.
  • He, Y.,Wang, Y., Liu, B., Helmling, C., Sušac, L., Cheng, R., Zhou, Z. H., & Feigon, J. (2021). Structures of telomerase at several steps of telomere repeat synthesis. Nature. 2021, May 12; 593(7859): 454–459. doi: 10.1038/s41586-021-03529-9.
  • He, Y., Y. Wang, B. Liu, C. Helmling, L. Susac, R. Cheng, H. Zhou and J. Feigon (2021). Structures of telomerase at several steps of telomere repeat synthesis. Nature. 593(7859): 454-459. doi: 10.1038/s41586-021-03529-9. Epub 2021 May 12. PMID: 33981033.
  • Ho, C.-M., Jih, J., Lai, M., Li, X., Goldberg, D. E., Beck, J. R., & Zhou, Z. H. (2021). Native structure of the Rhoph Complex, a key determinant of malaria parasite nutrient acquisition. Proceedings of the National Academy of Sciences. 2021: Aug 26; 118(35): e2100514118. doi: 10.1073/pnas.2100514118.
  • Huang, J., Peng, B., Stracensky, T., Liu, Z., Zhang, A., Xu, M., Liu, Y., Zhao, Z., Duan, X., Jia, Q., & Huang, Y. (2021). 1D PtCo nanowires as catalysts for pemfcs with low PT loading. Science China Materials. 2021, Sep 29; 65(3): 704–711. doi: 10.1007/s40843-021-1777-x.
  • Liu, Y.-T., Strugatsky, D., Liu, W., & Zhou, Z. H. (2021). Structure of human cytomegalovirus virion reveals host trna binding to capsid-associated tegument protein PP150. Nature Communications. 2021, Sep 17; 12(1): 5513. doi: 10.1038/s41467-021-25791-1.
  • Liu, Y.-T., Zhang, H., Wang, H., Tao, C.-L., Bi, G.-Q., & Zhou, Z. H. (2021). Isotropic reconstruction of electron tomograms with deep learning. bioRxiv. 2021, Jul 19. doi:10.1101/2021.07.17.452128.
  • Mecklenburg, M., Zutter, B. T., Ling, X. Y., Hubbard, W. A., & Regan, B. C. (2021). Visualizing the electron wind force in the elastic regime. Nano Letters. 2021, Dec 22; 21(24), 10172-10177. doi: 10.1021/acs.nanolett.1c02641.
  • Pan, M., Alvarez-Cabrera, A. L., Kang, J. S., Wang, L., Fan, C., & Zhou, Z. H. (2021). Asymmetric reconstruction of mammalian reovirus reveals interactions among RNA, transcriptional factor Μ2 and capsid proteins. Nature Communications. 2021, Jul 7; 12(1): 4176. doi: 10.1038/s41467-021-24455-4.
  • Sharma, A., Zhang, X., Dejnirattisai, W., Dai, X., Gong, D., Wongwiwat, W., Duquerroy, S., Rouvinski, A., Vaney, M.-C., Guardado-Calvo, P., Haouz, A., England, P., Sun, R., Zhou, Z. H., Mongkolsapaya, J., Screaton, G. R., & Rey, F. A. (2021). The epitope arrangement on flavivirus particles contributes to Mab C10’s extraordinary neutralization breadth across Zika and dengue viruses. Cell. 2021, Dec 9; 184(25): 6052-6066. doi: 10.1016/j.cell.2021.11.010.
  • Sharma, A., Zhang, X., Dejnirattisai, W., Dai, X., Gong, D., Wongwiwat, W., Duquerroy, S., Rouvinski, A., Vaney, M.-C., Guardado-Calvo, P., Haouz, A., England, P., Sun, R., Zhou, Z. H., Mongkolsapaya, J., Screaton, G. R., & Rey, F. A. (2021). The epitope arrangement on flavivirus particles contributes to Mab C10’s extraordinary neutralization breadth across Zika and dengue viruses. Cell. 2021, Dec 9; 184(25): 6052-6066. doi: 10.1016/j.cell.2021.11.010.
  • Stevens, A, K Muratore, Y Cui, PJ Johnson, ZH Zhou* (2021) Atomic Structure of the Trichomonas vaginalis Double-Stranded RNA Virus 2. Mbio 12 (2). PMCID: PMC8092272.
  • Stevens, A., Muratore, K., Cui, Y., Johnson, P. J., & Zhou, Z. H. (2021). Atomic structure of the Trichomonas vaginalis double-stranded RNA virus 2. MBio. 2021, Mar 30; 12(2): e02924-20. doi: 10.1128/mbio.02924-20.
  • Tanaka, K., Liao, M. E., Aleman, A., Zaid, H., Goorsky, M. S., & Kodambaka, S. (2021). Growth of heterolayered [cubic-tac(111) + rhombohedral-TA3C2(0001)] nanocomposite thin films on Al2O3(0001). Acta Materialia. 2021, Feb 1; 204: 1-9. doi: 10.1016/j.actamat.2020.116499.
  • TC Terwilliger, OV Sobolev, PV Afonine, PD Adams, CM Ho, X Li, H. Zhou. (2021) Protein identification from electron cryomicroscopy maps by automated model building and side-chain matching. Acta Crystallographica Section D: Structural Biology. 77 (4):457-462. doi: 10.1107/S2059798321001765. Epub 2021 Mar 30.
  • Wang, W., Tsirulnikov, K., Zhekova, H. R., Kayık, G., Khan, H. M., Azimov, R., Abuladze, N., Kao, L., Newman, D., Noskov, S. Y., Zhou, Z. H., Pushkin, A., & Kurtz, I. (2021). Publisher correction: Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE. Nature Communications. 2021, Oct 13; 12(1): 6083. doi: 10.1038/s41467-021-26412-7.
  • Woodson, M., Pajak, J., Mahler, B.P., Zhao, W., Zhang, W., Arya, G., White, M.A., Jardine, P.J., & Morais, M.C. (2021) A viral genome packaging motor transitions between cyclic and helical symmetry to translocate dsDNA. Sci Adv. 2021 May 7; 7(19):eabc1955. doi: 10.1126/sciadv.abc1955. PMID: 33962953. PMCID: PMC8104870.
  • Xia, X., Wu, W., Cui, Y., Roy, P., & Zhou, Z. H. (2021). Bluetongue virus capsid protein VP5 perforates membranes at low endosomal ph during viral entry. Nature Microbiology. 2021, Oct 26; 6(11): 1424–1432. doi: 10.1038/s41564-021-00988-8.
  • Xu, L., Zheng, Q., Zhu, R., Yin, Z., Yu, H., Lin, Y., Wu, Y., He, M., Huang, Y., Jiang, Y., Sun, H., Zha, Z., Yang, H., Huang, Q., Zhang, D., Chen, Z., Ye, X., Han, J., Yang, L., Liu, C., Que, Y., Fang, M., Gu, Y., Zhang, J., Luo, W., Zhou, Z. H.*, Li, S.*, Cheng, T.* & Xia, N.* Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell host & microbe, doi:10.1016/j.chom.2021.01.001 (2021).
  • Zhang J, Wang H, Imhof S, Zhou, X, Liao, S, Atanosov I, Hui WH, Hill KL* and Zhou ZH* (2021) Structure of the trypanosome paraflagellar rod and insights into non-planar motility of eukaryotic cells. Cell Discovery. In press. PMCID: in progress.
  • Zhang, J., Wang, H., Imhof, S., Zhou, X., Liao, S., Atanasov, I., Hui, W. H., Hill, K. L., & Zhou, Z. H. (2021). Author correction: Structure of the trypanosome paraflagellar rod and insights into non-planar motility of eukaryotic cells. Cell Discovery. 2021: Aug 6; 7(1): 61. doi: 10.1038/s41421-021-00317-7.
  • Zutter, B., Kim, H., Hubbard, W., Ren, D., Mecklenburg, M., Huffaker, D., & Regan, B. C.(2021). Mapping charge recombination and the effect of point-defect insertion in GaAs nanowire heterojunctions. Physical Review Applied. 2021, Oct 18; 16(4): 044030. doi: 10.1103/physrevapplied.16.044030.
  • Ge, P., D. Scholl, N. S. Prokhorov, J. Avaylon, M. M. Shneider, C. Browning, S. A. Buth, M. Plattner, U. Chakraborty, K. Ding, P. G. Leiman, J. F. Miller* and H. Zhou* (2020) Action of a minimal contractile bactericidal nanomachine. Nature. 2020;580(7805):658-662. doi:10.1038/s41586-020-2186-z. PMID: 32350467. PMC7513463 (featured on cover)
  • Hardenbrook NJ, Liu S, Zhou K, Ghosal K, Zhou ZH*, Krantz BA*. (2020) Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors. Nat Commun. 11(1):840. Published 2020 Feb 11. doi:10.1038/s41467-020-14658-6 PMID: 32047164 PMCID: PMC7012834.
  • He M, Xu L, Zheng Q, Zhu R, Yang L, Yin Z, Ye X, Li S, Hou W, Wu Y, Han J, Liu D, Lin Y, Li Z, Chen Z, Zha Z, Huang Y, Yu H, Que Y, Wang Y, Yan X, Zhang J, Ying G, Zhou ZH*, Cheng T*, Li S*, Xia N* (2020) Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16. Cell Host Microbe. 27(2):249-261.e5. doi:10.1016/j.chom.2020.01.003 PMID: 32027857
  • Sherman, M.B., Guenther, R., Reade, R., Rochon, D., Sit, T. & Smith, T. (2020) Near-atomic-resolution cryo-electron microscopy structures of cucumber leaf spot virus and red clover necrotic mosaic virus: evolutionary divergence at the icosahedral three-fold axes. J Virol. 2020 Jan 6; 94(2):e01439-19. doi: 10.1128/JVI.01439-19. Epub 2019 Nov 6. PMID: 31694952. PMCID: PMC6955255.
  • Leonard, D.*, Huang, W.*, Izadmehr, S., O’Connor, C.M., Wiredja, D., Wang, Z., Zaware, N., Chen, Y., Schlatzer, D., Kiselar, J., Vasireddi, N., Schuchner, S., Perl, A.L., Galsky, M., Xu, W., Brautigan, D., Ogris, E., Taylor, D.J., & Narla, G. (2020). Small molecule selectively enhances phosphatase function through biased heterotrimer stabilization. Cell. 2020 Apr 30; 181(3):688-701.e16. doi: 10.1016/j.cell.2020.03.038. In Press; Epub: April 20, 2020. PMID: 32315618. PMCID: PMC7243596 (available on 2021-04-30).
  • Mietzsch, M., McKenna, R., Väisänen, E., Yu, J. C., Ilyas, M., Hull, J. A., Kurian, J., Smith, J. K., Chipman, P., Lasanajak, Y., Smith, D., Söderlund-Venermo, M., & Agbandje-McKenna, M. (2020). Structural Characterization of Cuta- and Tusavirus: Insight into Protoparvoviruses Capsid Morphology. Viruses. 2020 Jun 17; 12(6):653. doi: 10.3390/v12060653. PMID: 32560452. PMCID: PMC7354515.
  • Pénzes, J. J., Pham, H. T., Chipman, P., Bhattacharya, N., McKenna, R., Agbandje-McKenna, M. & Tijssen, P. (2020). Molecular biology and structure of a novel penaeid shrimp densovirus elucidate convergent parvoviral host capsid evolution. Proc Natl Acad Sci U S A. 2020 Aug 18; 117(33):20211-20222. doi: 10.1073/pnas.2008191117. Epub 2020 Aug 3. PMID: 32747554. PMCID: PMC7443866.
  • Deniston, C.K., Salogiannis, J., Mathea, S., Snead, D.M., Lahiri, I., Matyszewski, M., Donorosa, O., Watanabe, R., Böhning, J., Shiau, A.K., Knapp, S., Villa, E., Reck-Peterson, S.L. & Leschziner, A.E. (2020) Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction. Nature. 2020 Dec 10; 588: 344-349. doi: 10.1038/s41586-020-2673-2. Epub 2020 Aug 19.
  • Mietzcsh, M., Li, Y., Kurian, J., Smith, J. K., Chipman, P., McKenna, R., Yang, L., & Agbandje-McKenna, M. (2020) Structural characterization of a bat Adeno-associated virus capsid. J Struct Biol. 2020 Aug 1;211(2);107547. doi: 10.1016/j.jsb.2020.107547. Epub 2020 Jun 6. PMID: 32522552.
  • Gann, E. R., Xian, Y., Abraham, P. E., Hettich, R. L., Reynolds, T. B., Xiao, C., & Wilhelm, S. W. (2020). Structural and Proteomic Studies of the Aureococcus anophagefferens virus demonstrate a global distribution of virus-encoded carbohydrate processing. Microbiol., 2020 Sept 8; 11, 2047. doi: 10.3389/fmicb.2020.02047. PMID: 33013751. PMCID: PMC7507832.
  • Atasheva, S., Emerson, C.C., Yao, J., Young, C., Stewart, P.L. & Shayakhmetov, D.M. (2020) Systematic cancer therapy with engineered adenovirus that evades innate immunity. Sci Transl Med. 2020 Nov 25; 12(571):eabc6659. doi: 10.1126/scitranslmed.abc6659.
  • Beren C, Cui Y, Chakravarty A, Yang X, Rao ALN*, Knobler CM, Zhou ZH*, and Gelbart WM*. Genome organization and interaction with capsid protein in a multipartite RNA virus. Proc Natl Acad Sci. 2020;117(20):10673-10680. doi:10.1073/pnas.1915078117. (2020) PMID: 32358197 PMCID: PMC7245085.
  • Zhou K, Liu S, Hardenbrook NJ, Cui Y, Krantz BA*, Zhou ZH* (2020) Atomic Structures of Anthrax Prechannel Bound with Full-Length Lethal and Edema Factors. Structure. 2020;28(8):879-887.e3. doi:10.1016/j.str.2020.05.009. PMID: 32521227. NIHMSID NIHMS1605756.
  • Chen, X., Y. Cui, H. Wang, H. Zhou, M. Gellert and W. Yang (2020). “How mouse RAG recombinase avoids DNA transposition.” Nature Structural & Molecular Biology 27(2): 127-133.
  • Chen X, Cui Y, Wang H, Zhou ZH, Yang W, Gellert M. Cutting antiparallel DNA strands in a single active site. Nat Struct Mol Biol, 2020;27(2):119-126. doi:10.1038/s41594-019-0363-2. PMID: 32015552 PMCID: PMC7015813.
  • Glynn, C., M. R. Sawaya, P. Ge, M. Gallagher-Jones, C. W. Short, R. Bowman, M. Apostol, H. Zhou, D. S. Eisenberg and J. A. Rodriguez (2020). “Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core.” Nat Struct Mol Biol. 27(5): 417-423. doi:10.1038/s41594-020-0403-y.
  • Das, S., P. Ge, Z. A. Oztug Durer, E. E. Grintsevich, Z. H. Zhou and E. Reisler (2020). “D-loop Dynamics and Near-Atomic-Resolution Cryo-EM Structure of Phalloidin-Bound F-Actin.” Structure 28(5): 586-593.e583. doi:10.1016/j.str.2020.04.004. PMID: 32348747 PMCID: PMC7316398.
  • Wang, B., Thurmond, S., Zhou, K., Sánchez-Aparicio, M. T., Fang, J., Lu, J., Gao, L., Ren, W., Cui, Y., Veit, E. C., Hong, H., Evans, M. J., O’Leary, S. E., García-Sastre, A., Zhou, Z. H.*, Hai, R.* & Song, J.* Structural basis for STAT2 suppression by flavivirus NS5. Nat Struct Mol Biol. 27, 875-885, doi:10.1038/s41594-020-0472-y (2020).
  • Liu, W., Y. Cui, C. Wang, Z. Li, D. Gong, X. Dai, G. Q. Bi, R. Sun and H. Zhou* (2020). Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus. Nat Microbiol. 2020;10.1038/s41564-020-0758-1. doi:10.1038/s41564-020-0758-1. PMID: 32719506 PMC7546529.
  • Liu YT, Shivakoti S, Jia F, Tao CL, Zhang B, Xu F, Lau PM, Bi GQ* and Zhou ZH*. Biphasic Exocytosis of Herpesvirus from Hippocampal Neurons and Mechanistic Implication to Membrane Fusion. Cell Disc. 2020;6:2. Published 2020 Jan 14. doi:10.1038/s41421-019-0134-6. PMID: 31969988 PMCID: PMC6957672
  • Yang, Y., Yang, P., Wang, N., Chen, Z., Su, D., Zhou, Z. H., Rao, Z. & Wang, X. Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation. Protein & Cell. 11, 339-351, doi:10.1007/s13238-020-00710-0 (2020). PMID: 32328903 PMC7196598.
  • Liu, Y. T., Tao, C. L., Zhang, X., Xia, W., Shi, D. Q., Qi, L., Xu, C., Sun, R., Li, X. W., Lau, P. M.*, Zhou, Z. H.* & Bi, G. Q.* Mesophasic organization of GABAA receptors in hippocampal inhibitory synapses. Nat Neurosci. 23, 1589-1596, doi:10.1038/s41593-020-00729-w (2020). PMCID: in progress, NIHMSID: 1678357.
  • Wang, W., Q. Zheng, D. Pan, H. Yu, W. Fu, J. Liu, M. He, R. Zhu, Y. Cai, Y. Huang, Z. Zha, Z. Chen, X. Ye, J. Han, Y. Que, T. Wu, J. Zhang, S. Li*, H. Zhu*, H. Zhou*, T. Cheng* and N. Xia* (2020). Near-atomic cryo-electron microscopy structures of varicella-zoster virus capsids [published online ahead of print, 2020 Sep 7]. Nat Microbiol. 2020;10.1038/s41564-020-0785-y. doi:10.1038/s41564-020-0785-y. PMID: 32895526 PMC7677223.
  • A., Mietzsch. M., Smith. J.K., Kurian, J., Chipman, P., McKenna, R., Chiorini, J., & Agbandje-McKenna, M. (2019) High-Resolution Structural Characterization of a New adeno-associated virus serotype 5 antibody epitope toward engineering antibody-resistant recombinant gene delivery vectors. J Virol. 93(1):e01394-18. doi: 10.1128/JVI.01394-18.
  • Liu W, Dai X, Jih J, Chan K, Trang P, Yu X, Balogun R, Mei Y, Liu F, Zhou ZH*. (2019) Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development. PLoS Pathog 15(2): e1007615. doi: 10.1371/journal.ppat.1007615. PMCID: PMC6396938
  • Liu, Y-T, Tao, C-L, Lau, P-M, Zhou, ZH, Bi, G-Q. (2019) Postsynaptic protein organization revealed by electron microscopy. Curr. Opion. Struct. Biol., 54:152-160. https://doi.org/10.1016/j.sbi.2019.02.012 GM071940
  • Tortorici, M.A., Walls, A.C., Lang, Y., Wang, C., Li, Z., Koerhuis, D., Boons, G., Bosch, B., Rey, F.A., de Groot, R.J., & Veesler D. (2019) Structural basis for human coronavirus attachment to sialic acid receptors. Nat Struct Mol Biol. 26(6): 481-489. doi: 10.1038/s41594-019-0233-y. PMID: 31160783. PMCID: PMC6554059. NIHMSID: NIHMS1527471.
  • Bennett A, Keravala A, Makal V, Kurian J, Belbellaa B, Aeran R, Tseng YS, Sousa D, Spear J, Gasmi M, Agbandje-McKenna M. Structure comparison of the chimeric AAV2.7m8 vector with parental AAV2. J Struct Biol. 2020 Feb 1;209(2):107433. doi: 10.1016/j.jsb.2019.107433. Epub 2019 Dec 16. PMID: 31859208. PMCID: PMC7058502.
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  •  Meng, H., Yang, S., Li, Z., Xia, T., Chen, J., Ji, Z., Zhang, H., Wang, X., Lin, S., Huang, C., Zhou, Z. H., Zink, J. I. and Nel, A. E. (2011) “Aspect Ratio Determines the Quantity of Mesoporous Silica Nanoparticle Uptake by a Small GTPase-Dependent Macropinocytosis Mechanism”, ACS Nano 5,4434-4447. PMCID: PMC3125420  
  • Ge, P. and Zhou, Z. H. (2011) “Hydrogen-bonding networks and RNA bases revealed by cryo electron microscopy suggest a triggering mechanism for calcium switches”, Proc Natl Acad Sci USA 108, 9637-9642. PMCID: PMC3111329 
  • Buehler, D. C., Toso, D. B., Kickhoefer, V. A., Zhou, Z. H. and Rome, L. H. (2011) “Vaults engineered for hydrophobic drug delivery”, Small. 7, 1432-1439. (featured on cover) PMID: 21506266
  • Yang, Z., Hu, W., Chen, K., Wang, J. Lux, R., Zhou, Z.H. and Shi, W. (2011) “Alanine 32 in PilA is important for PilA stability and type IV pili function in Myxococcus xanthus”. Microbiology, 157, 1920-1928. PMCID: PMC3167889
  • Zhang, X. and Zhou, Z.H. (2011) “Limiting factors in atomic resolution cryo electron microscopy – No simple tricks”. J. Struct. Biol., 175, 253-263.   PMCID: PMC3710782
  • Toso, D.B., Henstra, A.M., Gunsalus, R.P. and Zhou, Z.H. (2011) “Structural, mass, and elemental analyses of storage granules in methanogenic archaeal cells”, Environmental Microbiology, 13, 2587-2599. PMCID: PMC21854518.
  • “Yan, M., Du, J., Gu, Z., Liang, M., Hu, Y., Zhang, W., Priceman, S., Wu, L., Zhou, Z.H., Zheng. L., Segura, T., Tang, Y., Lu, Y. (2010) “A novel intracellular protein delivery platform based on single-protein nanocapsules“. Nature Nanotechnology, 5, 48 – 53. PMID: 19935648
  • Peng, L., Ryazantsev, S., Sun, R. and Zhou, Z. H. (2010) “Three-dimensional visualization of gammaherpesvirus life cycle in host cells by electron tomography“, Structure, 18, 47-58. (cover) PMCID: PMC2866045.
  • Ge P, Tsao, J., Schein, S., Green, T.J., Luo, M., Zhou, Z.H. (2010) “CryoEM model of the bullet-shaped vesicular stomatitis virus“. Science, 327, 689-693. PMCID: PMC2892700
  • Dai, W., Hodes, A., Wong, H. H., Gingery, M., Miller, J. F. and Zhou, Z. H. (2010) “Three-dimensional structure of tropism-switching Bordetella bacteriophage“, Proc Natl Acad Sci U S A 107, 4347-4352. PMCID: PMC2840154
  • Cheng, L., Zhu, J., Hui, W. H., Zhang, X., Honig, B., Fang, Q., Zhou, Z.H. (2010) “Backbone model of an aquareovirus virion by cryo-electron microscopy and bioinformatics“. J. Mol. Biol., 397, 852-863. (featured on cover) PMCID: PMC2900198
  • Zhang, X., M. Boyce, B. Bhattacharya, X. Zhang, S. Schein, P. Roy & Z. H. Zhou (2010) “Bluetongue virus coat protein VP2 contains sialic acid-binding domains, and VP5 resembles enveloped virus fusion proteins“, Proc Natl Acad Sci U S A 107, 6292-6297. PMCID: PMC2852009
  • Zhu, J., Cheng, L., Fang, Q., Zhou, Z.H.* and Honig, B.* (2010) “Building protein models with cryo-electron microscopy density maps based on homology modeling and multi-scale structure refinement“, J. Mol. Biol.  397, 835-851. (featured on cover)  PMCID: PMC2860449  *corresponding authors. 
  • Zhang, X., L. Jin, Q. Fang, W. H. Hui & Z. H. Zhou (2010) 3.3 “A cryo-EM structure of a nonenvelopedvirus reveals a priming mechanism for cell entry“, Cell 141, 472-482.    (featured on cover and CellPaperFlick Video of the issue) PMCID: PMC3412078
  • Faller, M., Toso, D., Matsunaga, M., Atanasov, I., Senturia, R., Chen, Y., Zhou, Z.H.*, Guo, F. * (2010) “DGCR8 recognizes primary transcripts of microRNAs through highly cooperative binding and formation of higher-order structures”. RNA, 16(8):1570-83. PMCID: PMC2905756      *corresponding authors
  • Zhang, X., Zhang, X., Zhou, Z.H. (2010) “Low cost, high Performance hybrid GPU-CPU solution for atomic resolution CryoEM single-particle reconstruction”. J.Struct. Biol., 172, 400-406. PMCID: PMC3382114
  • Huang, C.S., Sadre-Bazzaz, K., Shen, Y., Deng, B., Zhou, Z.H., Tong, L. (2010) “Crystal structure of the a6b6 holoenzyme of propionyl-coenzyme A carboxylase”. Nature, 466, 1001-1005. PMCID: PMC2925307
  • Liu, H., L. Jin, S. B. Koh, I. Atanasov, S. Schein, L. Wu & Z. H. Zhou (2010) “Atomic structure of human adenovirus by cryo-EM reveals interactions among protein networks”, Science 329, 1038-1043.  PMCID: PMC3412078
  • Jin, L., Pan, C., Qi, Z., Zhou, Z.H., Jiang, S. (2010) “Fab crystallization and preliminary X-ray analysis of NC-1, an anti-HIV-1 antibody that recognizes the six-helix bundle core of gp41″. Acta Cryst. F66, 854-857. PMCID: PMC2898479
  • Liu, S., J. He, C. Shih, K. Li, A. Dai, Z. H. Zhou & J. Zhang (2010) “Structural comparisons of hepatitis B core antigen particles with different C-terminal lengths”, Virus Res 149, 241-244. PMID: 20144668
  • Liu, J., Bradley, S.D., Howell, J.K., Zhou, Z.H., Norris, S.J. (2010) “Cellular architecture of Treponema pallidum: the syphilis spirochete“, J. Mol. Biol., 403, 546-561 (Cover) PMCID: PMC2957517
  • Leong, P. A., Yu, X., Zhou, Z. H., and Jensen, G. J. (2010). “Correcting for the ewald sphere in high-resolution single-particle reconstructions.” Methods Enzymol, 482, 369-380. PMCID: PMC3716286
  • Raines KS, Salha S, Sandberg RL, Jiang H, Rodríguez JA, Fahimian BP, Kapteyn HC, Du J, Miao J. “Three-dimensional structure determination from a single view.” Nature. 2010 Jan 14;463(7278):214-7. doi: 10.1038/nature08705. Epub 2009 Dec 16. 
  • Nayak, D. P., Balogun, R. A., Yamada, H., Zhou, Z. H., Barman, S. (2009). “Influenza virus morphogenesis and budding.” Virus Res. (2009), 143(2):147-61.
  • Pan, D., X. Wang, Zhou, Z. H., Chen, W.,  Xu, C., and Lu, Y. (2009) “Synthesis of quaternary semiconductor nanocrystals with tunable band gaps.” Chemistry of Materials, 21, 2489-2493. 
  • Li, F., Ge, P., Hui, W. H., Atanasov, I., Rogers, K., Guo, Q., Osato, D., Falick, A. M., Zhou, Z. H. and Simpson, L. (2009) “Structure of the core editing complex (L-Complex) involved in uridine insertion/deletion RNA editing in trypanosomatid mitochondria“, Proc Natl Acad Sci U S A 106,12306-12310. PMCID: PMC2708173.
  • Guo H, Wang L, Peng L, Zhou ZH, Deng H. (2009) “Open Reading Frame 33 of a gammaherpesvirusencodes a tegument protein essential for virion morphogenesis and egress“. J. Virol., 83, 10582-10595.
  • Song, C., Jiang, H.,  Mancuso, A., Amirbekian, B., Peng, L., Sun, R., Shah, S.S., Zhou, Z.H., Ishikawa, T. and Miao, J. (2008) “Quantitative and high-contrast imaging of single unstained viruses with coherent X-ray“, Phys. Rew. Let. 101, 158101-4