Electron Imaging Center for NanoMachines

EICN provides advanced electron imaging tools for applications ranging from materials science to structural biology 

Electron Imaging Center for Nanomachines

Publications

Users of the EICN Laboratory are requested to acknowledge their use of the Technology Centers at CNSI in their scholarly publications. All publications listed here included data acquired or generated in the EICN Laboratory.

  • Al Mamun, A. A., Wu, C., Chang, C., Sanchez, B. C., Das, A., & Ton-That, H. (2022). A cell wall-anchored glycoprotein confers resistance to cation stress in Actinomyces oris biofilms. Molecular Oral Microbiology. 2022, Mar 15; 37(5): 206–217. doi: 10.1111/omi.12365.
  • Bowler, J. T., Sawaya, M. R., Boyer, D. R., Cascio, D., Bali, M., & Eisenberg, D. S. (2022). Micro-electron diffraction structure of the aggregation-driving n terminus of drosophila neuronal protein orb2a reveals amyloid-like β-sheets.Journal of Biological Chemistry. 2022, Aug 18; 298(10): 102396. doi: 10.1016/j.jbc.2022.102396.
  • He, Y., Song, H., Chan, H., Liu, B., Wang, Y., Sušac, L., Zhou, Z. H., & Feigon, J. (2022). Structure of tetrahymena telomerase-bound CST with polymerase α-primase. Nature. 2022, Jul 13; 608(7924): 813–818. doi: 10.1038/s41586-022-04931-7.
  • Huang, J., Sementa, L., Liu, Z., Barcaro, G., Feng, M., Liu, E., Jiao, L., Xu, M., Leshchev, D., Lee, S.-J., Li, M., Wan, C., Zhu, E., Liu, Y., Peng, B., Duan, X., Goddard, W. A., Fortunelli, A., Jia, Q., & Huang, Y. (2022). Experimental Sabatier plot for predictive design of active and stable PT-alloy oxygen reduction reaction catalysts. Nature Catalysis. 2022, Jun 9; 5(6): 513–523. doi: 10.1038/s41929-022-00797-0.
  • Jiang, Y. X., Cao, Q., Sawaya, M. R., Abskharon, R., Ge, P., DeTure, M., Dickson, D. W., Fu, J. Y., Ogorzalek Loo, R. R., Loo, J. A., &Eisenberg, D. S. (2022). Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43. Nature. 2022, Mar 28; 605 (7909): 304–309. doi: 10.1038/s41586-022-04670-9.
  • Jiang, Y. X., Cao, Q., Sawaya, M. R., Abskharon, R., Ge, P., DeTure, M., Dickson, D. W., Fu, J. Y., Ogorzalek Loo, R. R., Loo, J. A., & Eisenberg, D. S. (2022). Amyloid fibrils in frontotemporal lobar degeneration with TDP-43 inclusions are composed of TMEM106B, rather than TDP-43. bioRxiv. 2022, Feb 1. doi:10.1101/2022.01.31.478523.
  • Jin Huang, Bosi Peng, Thomas Stracensky, Zeyan Liu, Ao Zhang, Mingjie Xu, Yang Liu, Zipeng Zhao, Xiangfeng Duan, Qingying Jia, & Yu Huang. 1D PtCo nanowires as catalysts for PEMFCs with low Pt loading.  China Mater. 65, 704–711 (2022). https://doi.org/10.1007/s40843-021-1777-x
  • Liu, B., He, Y., Wang, Y., Song, H., Zhou, Z. H., & Feigon, J. (2022). Structure of active human telomerase with telomere shelterin protein TPP1. Nature. 2022, Apr 13; 604(7906): 578–583. doi: 10.1038/s41586-022-04582-8.
  • Qi Qian, Huaying Ren, Jingyuan Zhou, Zhong Wan, Jingxuan Zhou, Xingxu Yan, Jin Cai, Peiqi Wang, Bailing Li, Zdenek Sofer, Bo Li, Xidong Duan, Xiaoqing Pan, Yu Huang, Xiangfeng Duan. Chiral molecular intercalation superlattices. Nature 606, 902–908 (2022). https://doi.org/10.1038/s41586-022-04846-3
  • Seidler, P. M., Murray, K. A., Boyer, D. R., Ge, P., Sawaya, M. R., Hu, C. J., Cheng, X., Abskharon, R., Pan, H., DeTure, M. A., Williams, C. K., Dickson, D. W., Vinters, H. V., & Eisenberg, D. S. (2022). Structure-based discovery of small molecules that disaggregate alzheimer’s disease tissue derived tau fibrils in vitro. Nature Communications. 2022, Sep 16; 13(1): 1-12. doi: 10.1038/s41467-022-32951-4.
  • Si, Z., Zhou, K., Tsao, J., Luo, M., & Zhou, Z. H. (2022). Locations and in situ structure of the polymerase complex inside the virion of vesicular stomatitis virus. Proceedings of the National Academy of Sciences.2022, Jul 2; 119(18): e2111948119. doi: 10.1073/pnas.2111948119
  • Tetreau, G., Sawaya, M. R., De Zitter, E., Andreeva, E. A., Banneville, A.-S., Schibrowsky, N. A., Coquelle, N., Brewster, A. S., Grünbein, M. L., Kovacs, G. N., Hunter, M. S., Kloos, M., Sierra, R. G., Schiro, G., Qiao, P., Stricker, M., Bideshi, D., Young, I. D., Rodriguez, J., … Colletier, J. P. (2022). De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals. Nature Communications. 2022, Jul 28; 13(1): 4376. doi: 10.1038/s41467-022-31746-x.
  • Yang, Y., Liu, S., Egloff, S., Eichhorn, C. D., Hadjian, T., Zhen, J., Kiss, T., Zhou, Z. H., & Feigon, J. (2022). Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP. Molecular Cell. 2022, May 5; 82(9): 1724-1736. doi: 10.1016/j.molcel.2022.03.001.
  • Zhekova, H. R., Wang, W., Tsirulnikov, K., Kayık, G., Khan, H. M., Azimov, R., Abuladze, N., Kao, L., Newman, D., Noskov, S., Tieleman, D. P.,Zhou, Z. H., Pushkin, A., & Kurtz, I. (2022). Insights Into the Na+-Dependent Anion Exchange in the SLC4 Family From the Cryo-EM Structure of the Sodium-Driven Chloride/Bicarbonate Exchanger SLC4A8. The FASEB Journal. 2022, May 13; 36(S1). doi: 10.1096/fasebj.2022.36.s1.r2784.
  • Cai, X., Liu, L., Qiu, C., Wen, C., He, Y., Cui, Y., Li, S., Zhang, X., Zhang, L., Tian, C., Bi, L., Zhou, Z. H., & Gong, W. (2021). Identification and architecture of a putative secretion tube across mycobacterial outer envelope. Science Advances. 2021, Aug 20; 7(34): eabg5656. doi: 10.1126/sciadv.abg5656.
  • He, Y., Song, H., Chan, H., Wang, Y., Liu, B., Susac, L., Zhou, Z. H., & Feigon, J.(2021). Structure of telomerase-bound CST with polymerase α-primase. bioRxiv. 2021, Dec 28. doi: 10.1101/2021.12.28.474374.
  • He, Y.,Wang, Y., Liu, B., Helmling, C., Sušac, L., Cheng, R., Zhou, Z. H., & Feigon, J. (2021). Structures of telomerase at several steps of telomere repeat synthesis. Nature. 2021, May 12; 593(7859): 454–459. doi: 10.1038/s41586-021-03529-9.
  • He, Y., Y. Wang, B. Liu, C. Helmling, L. Susac, R. Cheng, H. Zhou and J. Feigon (2021). Structures of telomerase at several steps of telomere repeat synthesis. Nature. 593(7859): 454-459. doi: 10.1038/s41586-021-03529-9. Epub 2021 May 12. PMID: 33981033.
  • Ho, C.-M., Jih, J., Lai, M., Li, X., Goldberg, D. E., Beck, J. R., & Zhou, Z. H. (2021). Native structure of the Rhoph Complex, a key determinant of malaria parasite nutrient acquisition. Proceedings of the National Academy of Sciences. 2021: Aug 26; 118(35): e2100514118. doi: 10.1073/pnas.2100514118.
  • Huang, J., Peng, B., Stracensky, T., Liu, Z., Zhang, A., Xu, M., Liu, Y., Zhao, Z., Duan, X., Jia, Q., & Huang, Y. (2021). 1D PtCo nanowires as catalysts for pemfcs with low PT loading. Science China Materials. 2021, Sep 29; 65(3): 704–711. doi: 10.1007/s40843-021-1777-x.
  • Liu, Y.-T., Strugatsky, D., Liu, W., & Zhou, Z. H. (2021). Structure of human cytomegalovirus virion reveals host trna binding to capsid-associated tegument protein PP150. Nature Communications. 2021, Sep 17; 12(1): 5513. doi: 10.1038/s41467-021-25791-1.
  • Liu, Y.-T., Zhang, H., Wang, H., Tao, C.-L., Bi, G.-Q., & Zhou, Z. H. (2021). Isotropic reconstruction of electron tomograms with deep learning. bioRxiv. 2021, Jul 19. doi:10.1101/2021.07.17.452128.
  • Mecklenburg, M., Zutter, B. T., Ling, X. Y., Hubbard, W. A., & Regan, B. C. (2021). Visualizing the electron wind force in the elastic regime. Nano Letters. 2021, Dec 22; 21(24), 10172-10177. doi: 10.1021/acs.nanolett.1c02641.
  • Pan, M., Alvarez-Cabrera, A. L., Kang, J. S., Wang, L., Fan, C., & Zhou, Z. H. (2021). Asymmetric reconstruction of mammalian reovirus reveals interactions among RNA, transcriptional factor Μ2 and capsid proteins. Nature Communications. 2021, Jul 7; 12(1): 4176. doi: 10.1038/s41467-021-24455-4.
  • Sharma, A., Zhang, X., Dejnirattisai, W., Dai, X., Gong, D., Wongwiwat, W., Duquerroy, S., Rouvinski, A., Vaney, M.-C., Guardado-Calvo, P., Haouz, A., England, P., Sun, R., Zhou, Z. H., Mongkolsapaya, J., Screaton, G. R., & Rey, F. A. (2021). The epitope arrangement on flavivirus particles contributes to Mab C10’s extraordinary neutralization breadth across Zika and dengue viruses. Cell. 2021, Dec 9; 184(25): 6052-6066. doi: 10.1016/j.cell.2021.11.010.
  • Sharma, A., Zhang, X., Dejnirattisai, W., Dai, X., Gong, D., Wongwiwat, W., Duquerroy, S., Rouvinski, A., Vaney, M.-C., Guardado-Calvo, P., Haouz, A., England, P., Sun, R., Zhou, Z. H., Mongkolsapaya, J., Screaton, G. R., & Rey, F. A. (2021). The epitope arrangement on flavivirus particles contributes to Mab C10’s extraordinary neutralization breadth across Zika and dengue viruses. Cell. 2021, Dec 9; 184(25): 6052-6066. doi: 10.1016/j.cell.2021.11.010.
  • Stevens, A, K Muratore, Y Cui, PJ Johnson, ZH Zhou* (2021) Atomic Structure of the Trichomonas vaginalis Double-Stranded RNA Virus 2. Mbio 12 (2). PMCID: PMC8092272.
  • Stevens, A., Muratore, K., Cui, Y., Johnson, P. J., & Zhou, Z. H. (2021). Atomic structure of the Trichomonas vaginalis double-stranded RNA virus 2. MBio. 2021, Mar 30; 12(2): e02924-20. doi: 10.1128/mbio.02924-20.
  • Tanaka, K., Liao, M. E., Aleman, A., Zaid, H., Goorsky, M. S., & Kodambaka, S. (2021). Growth of heterolayered [cubic-tac(111) + rhombohedral-TA3C2(0001)] nanocomposite thin films on Al2O3(0001). Acta Materialia. 2021, Feb 1; 204: 1-9. doi: 10.1016/j.actamat.2020.116499.
  • TC Terwilliger, OV Sobolev, PV Afonine, PD Adams, CM Ho, X Li, H. Zhou. (2021) Protein identification from electron cryomicroscopy maps by automated model building and side-chain matching. Acta Crystallographica Section D: Structural Biology. 77 (4):457-462. doi: 10.1107/S2059798321001765. Epub 2021 Mar 30.
  • Wang, W., Tsirulnikov, K., Zhekova, H. R., Kayık, G., Khan, H. M., Azimov, R., Abuladze, N., Kao, L., Newman, D., Noskov, S. Y., Zhou, Z. H., Pushkin, A., & Kurtz, I. (2021). Publisher correction: Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE. Nature Communications. 2021, Oct 13; 12(1): 6083. doi: 10.1038/s41467-021-26412-7.
  • Woodson, M., Pajak, J., Mahler, B.P., Zhao, W., Zhang, W., Arya, G., White, M.A., Jardine, P.J., & Morais, M.C. (2021) A viral genome packaging motor transitions between cyclic and helical symmetry to translocate dsDNA. Sci Adv. 2021 May 7; 7(19):eabc1955. doi: 10.1126/sciadv.abc1955. PMID: 33962953. PMCID: PMC8104870.
  • Xia, X., Wu, W., Cui, Y., Roy, P., & Zhou, Z. H. (2021). Bluetongue virus capsid protein VP5 perforates membranes at low endosomal ph during viral entry. Nature Microbiology. 2021, Oct 26; 6(11): 1424–1432. doi: 10.1038/s41564-021-00988-8.
  • Xu, L., Zheng, Q., Zhu, R., Yin, Z., Yu, H., Lin, Y., Wu, Y., He, M., Huang, Y., Jiang, Y., Sun, H., Zha, Z., Yang, H., Huang, Q., Zhang, D., Chen, Z., Ye, X., Han, J., Yang, L., Liu, C., Que, Y., Fang, M., Gu, Y., Zhang, J., Luo, W., Zhou, Z. H.*, Li, S.*, Cheng, T.* & Xia, N.* Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell host & microbe, doi:10.1016/j.chom.2021.01.001 (2021).
  • Zhang J, Wang H, Imhof S, Zhou, X, Liao, S, Atanosov I, Hui WH, Hill KL* and Zhou ZH* (2021) Structure of the trypanosome paraflagellar rod and insights into non-planar motility of eukaryotic cells. Cell Discovery. In press. PMCID: in progress.
  • Zhang, J., Wang, H., Imhof, S., Zhou, X., Liao, S., Atanasov, I., Hui, W. H., Hill, K. L., & Zhou, Z. H. (2021). Author correction: Structure of the trypanosome paraflagellar rod and insights into non-planar motility of eukaryotic cells. Cell Discovery. 2021: Aug 6; 7(1): 61. doi: 10.1038/s41421-021-00317-7.
  • Zutter, B., Kim, H., Hubbard, W., Ren, D., Mecklenburg, M., Huffaker, D., & Regan, B. C.(2021). Mapping charge recombination and the effect of point-defect insertion in GaAs nanowire heterojunctions. Physical Review Applied. 2021, Oct 18; 16(4): 044030. doi: 10.1103/physrevapplied.16.044030.
  • Ge, P., D. Scholl, N. S. Prokhorov, J. Avaylon, M. M. Shneider, C. Browning, S. A. Buth, M. Plattner, U. Chakraborty, K. Ding, P. G. Leiman, J. F. Miller* and H. Zhou* (2020) Action of a minimal contractile bactericidal nanomachine. Nature. 2020;580(7805):658-662. doi:10.1038/s41586-020-2186-z. PMID: 32350467. PMC7513463 (featured on cover)
  • Hardenbrook NJ, Liu S, Zhou K, Ghosal K, Zhou ZH*, Krantz BA*. (2020) Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors. Nat Commun. 11(1):840. Published 2020 Feb 11. doi:10.1038/s41467-020-14658-6 PMID: 32047164 PMCID: PMC7012834.
  • He M, Xu L, Zheng Q, Zhu R, Yang L, Yin Z, Ye X, Li S, Hou W, Wu Y, Han J, Liu D, Lin Y, Li Z, Chen Z, Zha Z, Huang Y, Yu H, Que Y, Wang Y, Yan X, Zhang J, Ying G, Zhou ZH*, Cheng T*, Li S*, Xia N* (2020) Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16. Cell Host Microbe. 27(2):249-261.e5. doi:10.1016/j.chom.2020.01.003 PMID: 32027857
  • Sherman, M.B., Guenther, R., Reade, R., Rochon, D., Sit, T. & Smith, T. (2020) Near-atomic-resolution cryo-electron microscopy structures of cucumber leaf spot virus and red clover necrotic mosaic virus: evolutionary divergence at the icosahedral three-fold axes. J Virol. 2020 Jan 6; 94(2):e01439-19. doi: 10.1128/JVI.01439-19. Epub 2019 Nov 6. PMID: 31694952. PMCID: PMC6955255.
  • Leonard, D.*, Huang, W.*, Izadmehr, S., O’Connor, C.M., Wiredja, D., Wang, Z., Zaware, N., Chen, Y., Schlatzer, D., Kiselar, J., Vasireddi, N., Schuchner, S., Perl, A.L., Galsky, M., Xu, W., Brautigan, D., Ogris, E., Taylor, D.J., & Narla, G. (2020). Small molecule selectively enhances phosphatase function through biased heterotrimer stabilization. Cell. 2020 Apr 30; 181(3):688-701.e16. doi: 10.1016/j.cell.2020.03.038. In Press; Epub: April 20, 2020. PMID: 32315618. PMCID: PMC7243596 (available on 2021-04-30).
  • Mietzsch, M., McKenna, R., Väisänen, E., Yu, J. C., Ilyas, M., Hull, J. A., Kurian, J., Smith, J. K., Chipman, P., Lasanajak, Y., Smith, D., Söderlund-Venermo, M., & Agbandje-McKenna, M. (2020). Structural Characterization of Cuta- and Tusavirus: Insight into Protoparvoviruses Capsid Morphology. Viruses. 2020 Jun 17; 12(6):653. doi: 10.3390/v12060653. PMID: 32560452. PMCID: PMC7354515.
  • Pénzes, J. J., Pham, H. T., Chipman, P., Bhattacharya, N., McKenna, R., Agbandje-McKenna, M. & Tijssen, P. (2020). Molecular biology and structure of a novel penaeid shrimp densovirus elucidate convergent parvoviral host capsid evolution. Proc Natl Acad Sci U S A. 2020 Aug 18; 117(33):20211-20222. doi: 10.1073/pnas.2008191117. Epub 2020 Aug 3. PMID: 32747554. PMCID: PMC7443866.
  • Deniston, C.K., Salogiannis, J., Mathea, S., Snead, D.M., Lahiri, I., Matyszewski, M., Donorosa, O., Watanabe, R., Böhning, J., Shiau, A.K., Knapp, S., Villa, E., Reck-Peterson, S.L. & Leschziner, A.E. (2020) Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction. Nature. 2020 Dec 10; 588: 344-349. doi: 10.1038/s41586-020-2673-2. Epub 2020 Aug 19.
  • Mietzcsh, M., Li, Y., Kurian, J., Smith, J. K., Chipman, P., McKenna, R., Yang, L., & Agbandje-McKenna, M. (2020) Structural characterization of a bat Adeno-associated virus capsid. J Struct Biol. 2020 Aug 1;211(2);107547. doi: 10.1016/j.jsb.2020.107547. Epub 2020 Jun 6. PMID: 32522552.
  • Gann, E. R., Xian, Y., Abraham, P. E., Hettich, R. L., Reynolds, T. B., Xiao, C., & Wilhelm, S. W. (2020). Structural and Proteomic Studies of the Aureococcus anophagefferens virus demonstrate a global distribution of virus-encoded carbohydrate processing. Microbiol., 2020 Sept 8; 11, 2047. doi: 10.3389/fmicb.2020.02047. PMID: 33013751. PMCID: PMC7507832.
  • Atasheva, S., Emerson, C.C., Yao, J., Young, C., Stewart, P.L. & Shayakhmetov, D.M. (2020) Systematic cancer therapy with engineered adenovirus that evades innate immunity. Sci Transl Med. 2020 Nov 25; 12(571):eabc6659. doi: 10.1126/scitranslmed.abc6659.
  • Beren C, Cui Y, Chakravarty A, Yang X, Rao ALN*, Knobler CM, Zhou ZH*, and Gelbart WM*. Genome organization and interaction with capsid protein in a multipartite RNA virus. Proc Natl Acad Sci. 2020;117(20):10673-10680. doi:10.1073/pnas.1915078117. (2020) PMID: 32358197 PMCID: PMC7245085.
  • Zhou K, Liu S, Hardenbrook NJ, Cui Y, Krantz BA*, Zhou ZH* (2020) Atomic Structures of Anthrax Prechannel Bound with Full-Length Lethal and Edema Factors. Structure. 2020;28(8):879-887.e3. doi:10.1016/j.str.2020.05.009. PMID: 32521227. NIHMSID NIHMS1605756.
  • Chen, X., Y. Cui, H. Wang, H. Zhou, M. Gellert and W. Yang (2020). “How mouse RAG recombinase avoids DNA transposition.” Nature Structural & Molecular Biology 27(2): 127-133.
  • Chen X, Cui Y, Wang H, Zhou ZH, Yang W, Gellert M. Cutting antiparallel DNA strands in a single active site. Nat Struct Mol Biol, 2020;27(2):119-126. doi:10.1038/s41594-019-0363-2. PMID: 32015552 PMCID: PMC7015813.
  • Glynn, C., M. R. Sawaya, P. Ge, M. Gallagher-Jones, C. W. Short, R. Bowman, M. Apostol, H. Zhou, D. S. Eisenberg and J. A. Rodriguez (2020). “Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core.” Nat Struct Mol Biol. 27(5): 417-423. doi:10.1038/s41594-020-0403-y.
  • Das, S., P. Ge, Z. A. Oztug Durer, E. E. Grintsevich, Z. H. Zhou and E. Reisler (2020). “D-loop Dynamics and Near-Atomic-Resolution Cryo-EM Structure of Phalloidin-Bound F-Actin.” Structure 28(5): 586-593.e583. doi:10.1016/j.str.2020.04.004. PMID: 32348747 PMCID: PMC7316398.
  • Wang, B., Thurmond, S., Zhou, K., Sánchez-Aparicio, M. T., Fang, J., Lu, J., Gao, L., Ren, W., Cui, Y., Veit, E. C., Hong, H., Evans, M. J., O’Leary, S. E., García-Sastre, A., Zhou, Z. H.*, Hai, R.* & Song, J.* Structural basis for STAT2 suppression by flavivirus NS5. Nat Struct Mol Biol. 27, 875-885, doi:10.1038/s41594-020-0472-y (2020).
  • Liu, W., Y. Cui, C. Wang, Z. Li, D. Gong, X. Dai, G. Q. Bi, R. Sun and H. Zhou* (2020). Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus. Nat Microbiol. 2020;10.1038/s41564-020-0758-1. doi:10.1038/s41564-020-0758-1. PMID: 32719506 PMC7546529.
  • Liu YT, Shivakoti S, Jia F, Tao CL, Zhang B, Xu F, Lau PM, Bi GQ* and Zhou ZH*. Biphasic Exocytosis of Herpesvirus from Hippocampal Neurons and Mechanistic Implication to Membrane Fusion. Cell Disc. 2020;6:2. Published 2020 Jan 14. doi:10.1038/s41421-019-0134-6. PMID: 31969988 PMCID: PMC6957672
  • Yang, Y., Yang, P., Wang, N., Chen, Z., Su, D., Zhou, Z. H., Rao, Z. & Wang, X. Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation. Protein & Cell. 11, 339-351, doi:10.1007/s13238-020-00710-0 (2020). PMID: 32328903 PMC7196598.
  • Liu, Y. T., Tao, C. L., Zhang, X., Xia, W., Shi, D. Q., Qi, L., Xu, C., Sun, R., Li, X. W., Lau, P. M.*, Zhou, Z. H.* & Bi, G. Q.* Mesophasic organization of GABAA receptors in hippocampal inhibitory synapses. Nat Neurosci. 23, 1589-1596, doi:10.1038/s41593-020-00729-w (2020). PMCID: in progress, NIHMSID: 1678357.
  • Wang, W., Q. Zheng, D. Pan, H. Yu, W. Fu, J. Liu, M. He, R. Zhu, Y. Cai, Y. Huang, Z. Zha, Z. Chen, X. Ye, J. Han, Y. Que, T. Wu, J. Zhang, S. Li*, H. Zhu*, H. Zhou*, T. Cheng* and N. Xia* (2020). Near-atomic cryo-electron microscopy structures of varicella-zoster virus capsids [published online ahead of print, 2020 Sep 7]. Nat Microbiol. 2020;10.1038/s41564-020-0785-y. doi:10.1038/s41564-020-0785-y. PMID: 32895526 PMC7677223.
  • A., Mietzsch. M., Smith. J.K., Kurian, J., Chipman, P., McKenna, R., Chiorini, J., & Agbandje-McKenna, M. (2019) High-Resolution Structural Characterization of a New adeno-associated virus serotype 5 antibody epitope toward engineering antibody-resistant recombinant gene delivery vectors. J Virol. 93(1):e01394-18. doi: 10.1128/JVI.01394-18.
  • Liu W, Dai X, Jih J, Chan K, Trang P, Yu X, Balogun R, Mei Y, Liu F, Zhou ZH*. (2019) Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development. PLoS Pathog 15(2): e1007615. doi: 10.1371/journal.ppat.1007615. PMCID: PMC6396938
  • Liu, Y-T, Tao, C-L, Lau, P-M, Zhou, ZH, Bi, G-Q. (2019) Postsynaptic protein organization revealed by electron microscopy. Curr. Opion. Struct. Biol., 54:152-160. https://doi.org/10.1016/j.sbi.2019.02.012 GM071940
  • Tortorici, M.A., Walls, A.C., Lang, Y., Wang, C., Li, Z., Koerhuis, D., Boons, G., Bosch, B., Rey, F.A., de Groot, R.J., & Veesler D. (2019) Structural basis for human coronavirus attachment to sialic acid receptors. Nat Struct Mol Biol. 26(6): 481-489. doi: 10.1038/s41594-019-0233-y. PMID: 31160783. PMCID: PMC6554059. NIHMSID: NIHMS1527471.
  • Bennett A, Keravala A, Makal V, Kurian J, Belbellaa B, Aeran R, Tseng YS, Sousa D, Spear J, Gasmi M, Agbandje-McKenna M. Structure comparison of the chimeric AAV2.7m8 vector with parental AAV2. J Struct Biol. 2020 Feb 1;209(2):107433. doi: 10.1016/j.jsb.2019.107433. Epub 2019 Dec 16. PMID: 31859208. PMCID: PMC7058502.
  • Zheng Q, Zhu R, Xu L, He M, Yan X, Liu D, Yin Z, Wu Y, Li Y, Yang L, Hou W, Li S, Li Z, Chen Z, Li Z, Yu H, Gu Y, Zhang J, Baker TS, Zhou ZH, Graham BS*, Cheng T*, Li S*, Xia N*. (2019) Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization. Microbiol., 4:124-133. doi: 10.1038/s41564-018-0275-7. PMCID: PMC6727974.
  • Gao Y, Cui Y, Fox T, Lin S, Wang H, de val Alda N, Zhou, ZH and Yang W. (2019) Structures and operating principles of the replisome. Science, 363 (6429) pii: eaav7003 doi: 10.1126/science.aav7003.
  • Cui Y, Zhou K, Strugatsky D, Wen Y, Sachs G, Zhou ZH*, Munson K. (2019) pH-dependent gating mechanism of the Helicobacter pylori urea channel revealed by cryo-EM. Sci Adv. 5(3):eaav8423. doi: 10.1126/sciadv.aav8423. PMCID: PMC6426461.
  • Kerviel A, Ge P, Lai M, Jih J, Boyce M, Zhang X, Zhou ZH*, Roy P* (2019) Atomic structure of the translation regulatory protein NS1 of bluetongue virus. Microbio. 4(5):837-845. doi: 10.1038/s41564-019-0369-x. PMCID: PMC6482088.
  • Ding K, Chang T, Shen W, Roy P*, Zhou ZH* (2019) In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release. Nat Commun. 10:2216. doi: 10.1038/s41467-019-10236-7. PMCID: PMC6525196.
  • Liu Y-T, Jih J, Dai X, Bi G-Q and Zhou ZH* (2019) Cryo-EM structures of herpes simplex virus type 1 portal vertex and packaged genome, Nature 570, 257–261. doi: 10.1038/s41586-019-1248-6. PMCID: PMC6732574.
  • Pumroy, RA., Samanta, A., Liu, Y., Hughes, TET., Zhao, S., Yudin, Y., Huynh, KW., Zhou, ZH, Rohacs, T., Han, S., and Moiseenkova-Bell VY. (2019, Jan 16). Molecular mechanism of TRPV2 channel modulation by cannabidiol. doi: 10.1101/521880.
  • Gong D, Dai X, Jih J, Liu YT, Bi GQ, Sun R*, Zhou ZH*. (2019) DNA-Packing Portal and Capsid-Associated Tegument Complexes in the Tumor Herpesvirus KSHV. Cell. 178(6):1329-1343.e12. doi: 10.1016/j.cell.2019.07.035. PMCID: PMC6753055
  • He Y, Shivakoti S, Ding K, Cui Y, Roy P, Zhou ZH*. (2019) In situ structures of RNA-dependent RNA polymerase inside bluetongue virus before and after uncoating. Proc Natl Acad Sci U S A. 116(33):16535-16540. doi:10.1073/pnas.1905849116. PMCID: PMC6697807.
  • Li X, Liu S, Zhang L, Issaian A, Hill RC, Espinosa S, Shi S, Cui Y, Kappel K, Das R, Hansen KC, Zhou ZH*, Zhao R*. 2019. A unified mechanism for intron and exon definition and back-splicing. Nature 573, 375–380 doi:10.1038/s41586-019-1523-6. PMID: 31485080. PMCID: PMC6939996.  
  • Wongpalee SP, Liu S, Gallego-Bartolomé J, Leitner A, Aebersold R, Liu W, Yen L, Nohales MA, Kuo PH, Vashisht AA, Wohlschlegel JA, Feng S, Kay SA, Zhou ZH*, Jacobsen SE* (2019) CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation. Nat Commun. 10(1):3916. doi:10.1038/s41467-019-11759-9. PubMed PMID: 31477705. PMCID: PMC6718625.
  • Ho C-M, Li X, Lai M, Terwilliger TC, Beck JR, Wohlschlegel J, Goldberg DE, Fitzpatrick AWP, Zhou ZH*. 2019 Bottom-up structural proteomics: cryoEM of protein complexes enriched from the cellular milieu. Nat Method. doi:10.1038/s41592-019-0637-y. PMCID: PMC7494424.
  • Cui Y, Zhang Y, Zhou K, Sun J*, Zhou ZH*. Conservative transcription in three steps visualized in a double-stranded RNA virus. Nat Struct Mol Biol. 2019 Nov;26(11):1023-1034. doi: 10.1038/s41594-019-0320-0. PMID: 31695188. PMCID PMC
  • Zhang Y, Liu W, Li Z, Kumar V, Alvarez-Cabrera AL, Leibovitch EC, Cui YC, Bi G-Q, Jacobson S, Zhou ZH* (2019) Atomic structure of the human herpesvirus 6B capsid and capsid-associated tegument complexes. Nat Commun. 10(1):5346. doi: 10.1038/s41467-019-13064-x. PMCID: PMC6877594.
  • Yang X, Clemens DL, Lee BY, Cui, Y, Zhou, ZH* and Horwitz MA* (2019) Atomic structure of the Francisella T6SS central spike reveals a unique α-helical lid and a putative cargo. Structure. 27(12):1811-1819.e6. doi:10.1016/j.str.2019.10.007. PMCID: PMC6939872.
  • Simon Imhof S, Zhang J, Wang H, Bui KH, Nguyen H, Atanosov I, Hui WH, Yang SK, Zhou ZH* and Hill KL* (2019) Cryo electron tomography reveals novel structural foundations of axoneme motility in the pathogen Trypanosoma brucei. eLife. 2019;8:e52058. doi:10.7554/eLife.52058. PMID: 31710293. PMCID: PMC6974359.
  • Olsen RW, Lindemeyer AK, Wallner M, Li X, Huynh KW, Zhou ZH. Cryo-electron microscopy reveals informative details of GABAAreceptor structural pharmacology: implications for drug discovery. Ann Transl Med. 2019;7(Suppl 3):S144. doi:10.21037/atm.2019.06.
  • Cao Q, Boyer DR, Sawaya MR, Ge P, Eisenberg DS. (2019) Cryo-EM structures of four polymorphic TDP-43 amyloid cores. Nat Struct Mol Biol. 26(7):619-627. doi: 10.1038/s41594-019-0248-4. PMCID: PMC7047951.
  • Warmack RA, Boyer DR, Zee CT, Richards LS, Sawaya MR, Cascio D, Gonen T, Eisenberg DS, Clarke SG (2019) Structure of amyloid-β (20-34) with Alzheimer’s-associated isomerization at Asp23 reveals a distinct protofilament interface. Nat Commun. 10(1):3357. doi: 10.1038/s41467-019-11183-z. PMCID: PMC6659688.
  • Liu Y, Huynh DT, Yeates TO. A 3.8 Å resolution cryo-EM structure of a small protein bound to an imaging scaffold. Nat Commun. 2019 Apr 23;10(1):1864. doi: 10.1038/s41467-019-09836-0. PMID: 31015551; PMCID: PMC6478846.
  • Hughes TET, Lodowski DT, Huynh KW, Yazici A, Del Rosario J, Kapoor A, Basak S, Samanta A, Han X, Chakrapani S, Zhou ZH, Filizola M, Rohacs T, Han S, Moiseenkova-Bell VY. “Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM”. Nat Struct Mol Biol. 2018 Jan;25(1):53-60. doi: 10.1038/s41594-017-0009-1. PubMed PMID: 29323279.
  • Ilyas M, Mietzsch M, Kailasan S, Väisänen E, Luo M, Chipman P, Smith JK, Kurian J, Sousa D, McKenna R, Söderlund-Venermo M, Agbandje-McKenna M. “Atomic Resolution Structures of Human Bufaviruses Determined by Cryo-Electron Microscopy“. Viruses. 2018 Jan 4;10(1). pii: E22. doi: 10.3390/v10010022. PubMed PMID: 29300333; PubMed Central PMCID: PMC5795435.
  • Snijder J, Ortego MS, Weidle C, Stuart AB, Gray MD, McElrath MJ, Pancera M, Veesler D, McGuire AT. “An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus”. Immunity. 2018 Apr 17;48(4):799-811.e9. doi: 10.1016/j.immuni.2018.03.026. PubMed PMID: 29669253; PubMed Central PMCID: PMC5909843.
  • Chen J, Zhu E, Liu J, Zhang S, Lin Z, Duan X, Heinz H, Huang Y, De Yoreo JJ. “Building two-dimensional materials one row at a time: Avoiding the nucleation barrier”. Science. 2018 Dec 7;362(6419):1135-1139. doi: 10.1126/science.aau4146. PMID: 30523105
  • Lin Z, Liu Y, Halim U, Ding M, Liu Y, Wang Y, Jia C, Chen P, Duan X, Wang C, Song F, Li M, Wan C, Huang Y, Duan X. “Solution-processable 2D semiconductors for high-performance large-area electronics”. Nature. 2018 Oct;562(7726):254-258. doi: 10.1038/s41586-018-0574-4. Epub 2018 Oct 3. PMID:
  • Yao B, Huang SW, Liu Y, Vinod AK, Choi C, Hoff M, Li Y, Yu M, Feng Z, Kwong DL, Huang Y, Rao Y, Duan X, Wong CW. “Gate-tunable frequency combs in graphene-nitride microresonators”. Nature. 2018 Jun;558(7710):410-414. doi: 10.1038/s41586-018-0216-x. Epub 2018 Jun 11.PMID:29892031
  • Liu Y, Guo J, Zhu E, Liao L, Lee SJ, Ding M, Shakir I, Gambin V, Huang Y, Duan X. “Approaching the Schottky-Mott limit in van der Waals metal-semiconductor junctions”. Nature. 2018 May;557(7707):696-700. doi: 10.1038/s41586-018-0129-8. Epub 2018 May 16. PMID: 29769729
  • Liu Z, Liu J, Wu HB, Shen G, Le Z, Chen G, Lu Y. “Iron-decorated nitrogen-rich carbons as efficient oxygen reduction electrocatalysts for Zn-air batteries”. Nanoscale. 2018 Sep 20;10(36):16996-17001. doi: 10.1039/c8nr04627a.
  • Lo YH, Zhao L, Gallagher-Jones M, Rana A, J Lodico J, Xiao W, Regan BC, Miao J. “In situ coherent diffractive imaging“. Nat Commun. 2018 May 8;9(1):1826. doi: 10.1038/s41467-018-04259-9.
  • White ER, Lodico JJ, Regan BC. “Intercalation events visualized in single microcrystals of graphite”. Nat Commun. 2017 Dec 6;8(1):1969. doi: 10.1038/s41467-017-01787-8. Erratum in: Nat Commun. 2018 Feb 19;9(1):759.
  • Chen NY, Kim P, Weston TA, Edillo L, Tu Y, Fong LG, Young SG. “Fibroblasts lacking nuclear lamins do not have nuclear blebs or protrusions but nevertheless have frequent nuclear membrane ruptures“. Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10100-10105. doi: 10.1073/pnas.1812622115. Epub 2018 Sep 17
  • Kim PH, Luu J, Heizer P, Tu Y, Weston TA, Chen N, Lim C, Li RL, Lin PY, Dunn JCY, Hodzic D, Young SG, Fong LG. “Disrupting the LINC complex in smooth muscle cells reduces aortic disease in a mouse model of Hutchinson-Gilford progeria syndrome”. Sci Transl Med. 2018 Sep 26;10(460). pii: eaat7163. doi: 10.1126/scitranslmed.aat7163
  • Sandhu J, Li S, Fairall L, Pfisterer SG, Gurnett JE, Xiao X, Weston TA, Vashi D, Ferrari A, Orozco JL, Hartman CL, Strugatsky D, Lee SD, He C, Hong C, Jiang H, Bentolila LA, Gatta AT, Levine TP, Ferng A, Lee R, Ford DA, Young SG, Ikonen E, Schwabe JWR, Tontonoz P. “Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells”. Cell. 2018 Oct 4;175(2):514-529.e20. doi: 10.1016/j.cell.2018.08.033. Epub 2018 Sep 13.
  • He C, Hu X, Weston TA, Jung RS, Sandhu J, Huang S, Heizer P, Kim J, Ellison R, Xu J, Kilburn M, Bensinger SJ, Riezman H, Tontonoz P, Fong LG, Jiang H, Young SG. “Macrophages release plasma membrane-derived particles rich in accessible cholesterol”. Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8499-E8508. doi: 10.1073/pnas.1810724115. Epub 2018 Aug 20
  • Huynh KW, Jiang J, Abuladze N, Tsirulnikov K, Kao L, Shao X, Newman D, Azimov R, Pushkin A, Zhou ZH*, Kurtz I.* (2018) “CryoEM structure of the human sodium-coupled acid-base transporter NBCe1″. Nature Communication. 9(1):900. doi: 10.1038/s41467-018-03271-3. PMCID: PMC5834491
  • Hughes TET, Lodowski DT, Huynh KW, Yazici A, Samanta A, Basak S, Zhou ZH, Rohacs T, Han S, Moiseenkova-Bell VY*. (2018) “Structural basis of the TRPV5 channel inhibition revealed by cryo-EM”. Nat Struct Mol. Biol. 25(1):53-60. doi: 10.1038/s41594-017-0009-1. PMCID: PMC5951624
  • Guenther EL, Ge P, Trinh H, Sawaya MR, Cascio D, Boyer DR, Gonen T, Zhou ZH, Eisenberg DS. (2018) “Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2“. Nat Struct Mol Biol. 25(4):311-319. doi: 10.1038/s41594-018-0045-5. PMID: 29531287
  • Dai X., Gong D., Lim H., Jih J., Wu T.T., Sun R.*, & Zhou Z.H.* (2018) “Structure and mutagenesis reveal capsid protein interactions essential to KSHV replication”. Nature. 553:521-525. [Featured the “research highlights” section of Nature Chemical Biology, Vol. 14 2018 (p199)]  PMCID: PMC6039102  
  •  Ding, K, Zhang, X, Mrazek, J, Kickhoefer, VA, Lai, M, Ng, HL, Yang, OY, Rome, LH and Zhou, ZH*. (2018) “Solution structures of engineered vault particles“. Structure. 26(4):619-626.e3. doi: 10.1016/j.str.2018.02.014.
  • Dai X. & Zhou Z.H.* (2018) “Structure of the herpes simplex virus-1 capsid with associated tegument protein complexes“. Science. 360, 48, eaao7298. DOI: 10.1126/science.aao7298. PMCID: PMC5959011.
  • Park K, Kuo Y, Shvadchak V, Ingargiola A, Dai X, Hsiung L, Kim W, Zhou H, Zou P, Levine AJ, Li J, Weiss S (2018) “Membrane insertion of-and membrane potential sensing by-semiconductor voltage nanosensors: Feasibility demonstration“. Sci Adv. 4(1):e1601453. doi: 10.1126/sciadv.1601453  PMCID: PMC5770167
  • Tao CL, Liu YT, Sun R, Zhang B, Qi L, Shivakoti S, Tian CL, Zhang P, Lau PM, Zhou ZH*, Bi GQ*. (2018) “Differentiation and Characterization of Excitatory and Inhibitory Synapses by Cryo-electron Tomography and Correlative Microscopy”. J Neurosci. 38(6):1493-1510. doi: 10.1523/JNEUROSCI.1548-17.2017. Epub 2018 Jan 8. PubMed PMID: 29311144; PubMed Central PMCID: PMC5815350.
  • Su Z, Wu C, Shi L, Luthra P, Pintilie GD, Johnson B, Porter JR, Ge P, Chen M, Liu G, Frederick TE, Binning JM, Bowman GR, Zhou ZH, Basler CF, Gross ML, Leung DW, Chiu W*, Amarasinghe GK* (2018) “Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly”. Cell. 2018 Feb 22;172(5):966-978.e12. doi: 10.1016/j.cell.2018.02.009.
  • Tian T, Li X, Liu Y, Wang C, Liu X, Bi G, Zhang X*, Yao X*, Zhou ZH*, Zang J*. “Molecular basis for CENP-N recognition of CENP-A nucleosome on the human kinetochore”. Cell Res. 2018 Mar;28(3):374-378. doi: 10.1038/cr.2018.13. Epub 2018 Jan 19. PubMed PMID: 29350209; PMCID: PMC5835772.
  • Kim MS, Chuenchor W, Chen X, Cui Y, Zhang X, Zhou ZH, Gellert M, Yang W. “Cracking the DNA Code for V(D)J Recombination”. Mol Cell. 2018 Mar 29. pii: S1097-2765(18)30189-8.doi: 10.1016/j.molcel.2018.03.008. PMCID: PMC5987255
  • Jiang, J., Wang, Y., Susac, L., Chan, H., Basu, R., Zhou, Z.H.* and Feigon, J.* (2018) “Structure of telomerase with telomeric DNA”. Cell. 173:1179-1190.e13. doi: 10.1016/j.cell.2018.04.038. PMCID: PMC5995583
  • Jiang J, Baiesc FL, Hiromasa Y, Yu X, Hui WH, Dai X, Roche TE, Zhou, ZH (2018) “Atomic Structure of the E2 Inner Core of Human Pyruvate Dehydrogenase Complex”. Biochemistry, 57(16):2325-2334. doi: 10.1021/acs.biochem.8b00357. PMCID: PMC6033517. 
  • Tao CL, Liu YT, Zhou ZH, Lau PM,Bi GQ*. (2018) “Accumulation of dense core vesicles in hippocampal synapses following chronic inactivity“. Frontiers in Neuroanatomy. doi: 10.3389/fnana.2018.00048. eCollection 2018. PMCID: PMC6004418. 
  • Ho, C, Beck, JR, Lai, ML, Cui, Y, Goldberg, DE, Egea, PF*, Zhou, ZH* (2018) “Malaria parasite translocon structure and mechanism of effector export“. Nature, 561(7721):70-75. doi: 10.1038/s41586-018-0469-4.
  • Li B, Ge P, Murray KA, Sheth P, Zhang M, Nair G, Sawaya MR, Shin WS, Boyer D, Ye S, Eisenberg DS*, Zhou ZH*, Jiang L* (2018) “Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel”. Nat. Commun. 9(1):3609. doi: 10.1038/s41467-018-05971-2. PMCID: PMC6127345
  • Yu I, Nguyen L, Avaylon J, Wang K, Lai M and Zhou ZH. “Building atomic models based on near atomic resolution cryoEM maps with existing tools”. J. Struct Biol. 2018 Nov;204(2):313-318. doi: 10.1016/j.jsb.2018.08.004.
  • Ding K, Nguyen L, Zhou ZH*. (2018) “In situ structures of polymerase complex and RNA genome show how aquareovirus transcription machineries respond to uncoating“. J Virol. 92(21). pii: e00774-18. doi: 10.1128/JVI.00774-18. PMCID: PMC6189512.
  • Zhu R, Xu L, Zheng Q, Cui Y, Li S, He M, Yin Z, Liu D, Li S, Li Z, Chen Z, Yu H, Que Y, Liu C, Kong Z, Zhang J, Baker TS, Yan X, Zhou ZH*, Cheng T*, Xia N* (2018) “Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10“. Sci. Adv.4(9):eaat7459. doi: 10.1126/sciadv.aat7459. 
  • Kappel K, Liu S, Larsen KP, Skiniotis G, Puglisi EV, Puglisi JD, Zhou ZH, Zhao R, Das R. (2018) “De novo computational RNA modeling into cryoEM maps of large ribonucleoprotein complexes”. Nature Method. 15(11):947-954. doi: 10.1038/s41592-018-0172-2.
  • Liu S, Xu L, Guan F, Liu YT, Cui Y, Zhang Q, Zheng X, Bi GQ, Zhou ZH*, Zhang X*, Ye S* (2018) “Cryo-EM structure of the human α5β3 GABA(A) receptor“. Cell Res. 28(9):958-961. doi: 10.1038/s41422-018-0077-8. PMID:30140029; PMCID: PMC6123483.
  • Hughes TET, Pumroy RA, Yazici AT, Kasimova MA, Fluck EC, Huynh KW, Samanta A, Molugu SK, Zhou ZH, Carnevale V, Rohacs T, Moiseenkova-Bell VY (2018) “Structural insights on TRPV5 gating by endogenous modulators”. Nat Commun. 9(1):4198. doi: 10.1038/s41467-018-06753-6. PMCID: PMC6179994. 
  • Pittman N, Misseldine A, Geilen L, Halder S, Smith JK, Kurian J, Chipman P, Janssen M, Mckenna R, Baker TS, D’Abramo A Jr, Cotmore S, Tattersall P, Agbandje-McKenna M. “Atomic Resolution Structure of the Oncolytic Parvovirus LuIII by Electron Microscopy and 3D Image Reconstruction. Viruses“. 2017 Oct 30;9(11).pii: E321. doi: 10.3390/v9110321. PubMed PMID: 29084163; PubMed Central PMCID: PMC5707528. https://www.ncbi.nlm.nih.gov/pubmed/29084163
  • Walls AC, Tortorici MA, Snijder J, Xiong X, Bosch BJ, Rey FA, Veesler D. “Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion“. Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11157-11162. doi: 10.1073/pnas.1708727114. Epub 2017 Oct 3. PubMed PMID: 29073020; PMCID: PMC5651768.
  • Sun H, Mei L, Liang J, Zhao Z, Lee C, Fei H, Ding M, Lau J, Li M, Wang C, Xu X, Hao G, Papandrea B, ShakirI, Dunn B, Huang Y, Duan X. “Three-dimensional holey-graphene/niobia composite architectures for ultrahigh-rate energy storage“. Science. 2017 May 12;356(6338):599-604. doi: 10.1126/science.aam5852. PMID: 28495745
  • Zhang X, Xu D, Jin X, Liu G, Liang S, Wang H, Chen W, Zhu X, Lu Y. “Nanocapsules of therapeutic proteins with enhanced stability and long blood circulation for hyperuricemia management“. J Control Release. 2017 Jun 10;255:54-61. doi: 10.1016/j.jconrel.2017.03.019. Epub 2017 Mar 11
  • Mayle KM, Dern KR, Wong VK, Sung S, Ding K, Rodriguez AR, Taylor Z, Zhou ZH, Grundfest WS, Deming TJ, Kamei DT. “Polypeptide-Based Gold Nanoshells for Photothermal Therapy“. SLAS Technol. (2017) 22(1):18-25. doi: 10.1177/2211068216645292.  PMID: 27126980  PMCID: PMC6070380
  • Dai, X, Li, X, Lai, M, Shu, S, Du, Y, Zhou, ZH* and Sun, R* (2017). “In situ structures of the genome and genome-delivery apparatus in an ssRNA virus“. Nature. 541(7635):112-116. doi: 10.1038/nature20589. *corresponding authors PMCID: PMC5701785
  • Yu, X, Jih, J, Jiang, J and Zhou, ZH* (2017) “Atomic structure of the human cytomegalovirus capsid with its securing tegument layer of pp150“, Science, 356. 1350. doi: 10.1126/science.aam6892. PMC5715728
  • Li J, He Q, Liu Y, Liu S, Tang S, Li C, Sun D, Li X, Zhou M, Zhu P, Bi G, Zhou Z, Zheng JS, Tian C.* “Chemical Synthesis of K34-Ubiquitylated H2B for Nucleosome Reconstitution and Single-Particle Cryo-Electron Microscopy Structural Analysis“. Chembiochem. 2017. 18(2):176-180. doi: 10.1002/cbic.201600551
  • Li X, Liu S, Jiang J, Zhang L, Espinosa S, Hill RC, Hansen KC, Zhou ZH*, Zhao R*. (2017) “CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing”. Nat Commun. 8(1):1035. doi: 10.1038/s41467-017-01241-9. PMID: 29051543
  • Xu L, Zheng Q, Li S, He M, Wu Y, Li Y, Zhu R, Yu H, Hong Q, Jiang J, Li Z, Li S, Zhao H, Yang L, Hou W, Wang W, Ye X, Zhang J, Baker TS, Cheng T, Zhou ZH, Yan X, Xia N.* (2017) “Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody”.  Nat Commun. 8(1):505. doi: 10.1038/s41467-017-00477-9.  PMID: 28894095  PMCID: PMC5593947
  • Liu YT, Jiang J, Bohannon KP, Dai X, Gant Luxton GW, Hui WH, Bi GQ, Smith GA, Zhou Z.H.*  (2017) A pUL25 dimer interfaces the pseudorabies virus capsid and tegument”. J Gen Virol. doi: 10.1099/jgv.0.000903. PMID: 29035172. PMCID: PMC5718256
  • Dai X, Wu L, Sun R, Zhou ZH.* (2017) “Atomic Structures of Minor Proteins VI and VII in the Human Adenovirus”. J. Virol. pii: JVI.00850-17. doi: 10.1128/JVI.00850-17. PMID: 28978703 PMCID: PMC5709574
  • Alewijnse, B., Ashton, A. W., Chambers, M. G., Chen, S., Cheng, A., Ebrahim, M., Eng, E., J H Hagen, W., Koster, A. J., Lopez, C. S., Lukoyanova, N., Ortega, J., Renault, L., Reyntjens, S., Rice, W. J., Scapin, G., Schrijver, R., Siebert, A., Stagg, S. M., Grum-Tokars, V., Wright, E. R., Wu, S., Yu, Z., Zhou, Z.H., Carragher, B., and S Potter, C.* (2017). “Best practices for managing large CryoEM facilities”. J Struct Biol 199(3): 225 – 236. PMID: 28827185. PMCID: PMC5605453
  • Sun Y, Wollenberg AL, O’Shea TM, Cui Y, Zhou ZH, Sofroniew MV, Deming TJ*. (2017) “Conformation-Directed Formation of Self-Healing Diblock Copolypeptide Hydrogels viaPolyion Complexation”. J Am Chem Soc. 139(42):15114-15121. doi: 10.1021/jacs.7b08190. PMID: 28976744 NIHMSID978645
  • Mayle KM, Dern KR, Wong VK, Chen KY, Sung S, Ding K, Rodriguez AR, Knowles S, Taylor Z, Zhou ZH, Grundfest WS, Wu AM, Deming TJ, Kamei DT. (2017) “Engineering A11Minibody-Conjugated, Polypeptide-Based Gold Nanoshells for Prostate Stem Cell Antigen (PSCA)-Targeted Photothermal Therapy“. SLAS Technol. 22(1):26-35. doi: 10.1177/2211068216669710
  • Wong JJW, Young TA, Zhang J, Liu S, Leser GP, Komives EA, Lamb RA, Zhou ZH, Salafsky J, Jardetzky TS*. (2017) “Monomeric ephrinB2 binding induces allosteric changes inNipah virus G that precede its full activation“. Nat Commun. 8(1):781. doi: 10.1038/s41467-017-00863-3. PMID: 28974687 PMCID:
  • Sathiyamoorthy K, Jiang J, Möhl BS, Chen J, Zhou ZH, Longnecker R, Jardetzky TS*. (2017) “Inhibition of EBV-mediated membrane fusion by anti-gHgL antibodies“. Proc Natl Acad Sci U S A. 114(41):E8703-E8710. doi: 10.1073/pnas.1704661114.  PMID: 28939750  PMCID:
  • Grintsevich, EE, Ge, P, Sawaya, MR, Yesilyurt, HG, Terman, HR*, Zhou, ZH*, Reisler, E* (2017) “Catastrophic disassembly of actin filaments via Mical-mediated oxidation”. Nature Communication, 8:2183. Doi:10.1038/s41467-017-02357-8. PMCID: PMC5736627 
  • Liu S, Li X, Zhang L, Jiang J, Hill RC, Cui, Y, Hansen KC, Zhou ZH*, Zhao R*. (2017) “Structure of the yeast spliceosomal postcatalytic P complex“. Science. pii: eaar3462. doi: 10.1126/science.aar3462. 358(6368):1278-1283. PMCID: PMC5828012. PMID: 29146870
  • Walls AC, Tortorici MA, Frenz B, Snijder J, Li W, Rey FA, DiMaio F, Bosch BJ, Veesler D. “Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy“. Nat Struct Mol Biol. 2016 Oct;23(10):899-905. doi: 10.1038/nsmb.3293. Epub 2016 Sep 12. PubMed PMID:27617430; PubMed Central PMCID: PMC5515730.
  • Li M, Zhao Z, Cheng T, Fortunelli A, Chen CY, Yu R, Zhang Q, Gu L, Merinov BV, Lin Z, Zhu E, Yu T, Jia Q, Guo J, Zhang L, Goddard WA 3rd, Huang Y, Duan X. “Ultrafine jagged platinum nanowires enable ultrahigh mass activity for the oxygen reduction reaction”. Science. 2016 Dec 16;354(6318):1414-1419. Epub 2016 Nov 17. PMID: 27856847
  • Zhao Z, Feng M, Zhou J, Liu Z, Li M, Fan Z, Tsen O, Miao J, Duan X, Huang Y. Composition tunable ternary Pt-Ni-Co octahedra for optimized oxygen reduction activity. Chem Commun (Camb). 2016 Sep 13;52(75):11215-11218. PMID: 27722573
  • Yin A, He Q, Lin Z, Luo L, Liu Y, Yang S, Wu H, Ding M, Huang Y, Duan X. “Plasmonic/Nonlinear Optical Material Core/Shell Nanorods as Nanoscale Plasmon Modulators and Optical Voltage Sensors”. Angew Chem Int Ed Engl. 2016 Jan 11;55(2):583-7. doi: 10.1002/anie.201508586. Epub 2015 Nov 24. Erratum in: Angew Chem Int Ed Engl. 2017 Mar 20;56(13):3414. PMID: 26783058
  • Zhang, X, Patel, A, Celma, CC, Yu, X, Roy, P, Zhou, ZH (2016) “Atomic model of a non-enveloped virus reveals pH sensors for a coordinated process of cell entry”. Nat. Struct. Mol. Biol. 23:74-80. doi:10.1038/nsmb.3134. PMID: 26641711. PMCID: PMC5669276
  • Gunsalus RP, Cook LE, Crable B, Rohlin L, McDonald E, Mouttaki H, Sieber JR, Poweleit N, Zhou H, Lapidus AL, Daligault HE, Land M, Gilna P, Ivanova N, Kyrpides N, Culley DE, McInerney MJ. “Complete genome sequence of Methanospirillum hungatei type strain JF1.Stand Genomic Sci”.2016 Jan 6;11:2. doi: 10.1186/s40793-015-0124-8.
  • Huynh KW, Cohen MR, Jiang J, Samanta A, Lodowski DT, Zhou ZH, Moiseenkova-Bell VY (2016) “Structure of the full-length TRPV2 channel by cryo-EM”. Nature Communication, 7:11130. doi: 10.1038/ncomms11130.
  • Huber RC, Ferreira AS, Aguirre JC, Kilbride D, Toso DB, Mayoral K, Zhou ZH, Kopidakis N, Rubin Y, Schwartz BJ, Mason TG, Tolbert SH. “On the Structure and Conductivity of Semiconducting Polymer Hydrogels”. J Phys Chem B. 2016. 120(26):6215-24. doi: 10.1021/acs.jpcb.6b02202. PMID: 27079171.
  • Toso DB, Javed MM, Czornyj E, Gunsalus RP, and Zhou ZH “Discovery and Characterization of iron sulfide and polyphosphate bodies coexisting in Archaeoglobus fulgidus cells”, Archaea, Volume 2016 (2016), Article ID 4706532, http://dx.doi.org/10.1155/2016/4706532  
  • Zhou, ZH, Hui, WH, Zhang, J, Atanasov, I, Celma, CC, Roy, P. “In situ structure of viral RNA by cryo electron tomography with Volta phase plate, energy filtering and direct electron counting.Microscopy and Microanalysis”. 22, S3, 2016, DOI: https://doi.org/10.1017/S1431927616001227.
  • Poweleit N, Ge P, Nguyen HH, Loo RR, Gunsalus RG, Zhou ZH. “CryoEM structure of the Methanospirillum hungatei archaellum reveals structural features distinct from the bacterial flagellum and type IV pilus”. Nature Microbiology. 2016; 2:16264. doi: 10.1038/nmicrobiol.2016.264. PMCID: PMC5695567
  • Zhang X, Lai M, Chang W, Yu I, Ding K, Mrazek J, Ng HL, Yang OO, Maslov DA, Zhou ZH. “Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes”. Nat Commun. 2016 Oct 18;7:13223. doi: 10.1038/ncomms13223. PMCID: PMC5071889
  • Bor B, Poweleit N, Bois JS, Cen L, Bedree JK, Zhou ZH, Gunsalus RP, Lux R, McLean JS, He X, Shi W. (2016) “Phenotypic and Physiological Characterization of the Epibiotic Interaction Between TM7x and Its Basibiont Actinomyces”. Microb Ecol. 2016 Jan;71(1):243-55. doi: 10.1007/s00248-015-0711-7. Epub 2015 Nov 23. PMCID: PMC4688200
  • Huang X, Zhao Z, Cao L, Chen Y, Zhu E, Lin Z, Li M, Yan A, Zettl A, Wang YM, Duan X, Mueller T, Huang Y. “ELECTROCHEMISTRY. High-performance transition metal-doped Pt₃Ni octahedra for oxygen reduction reaction”. Science. 2015 Jun 12;348(6240):1230-4. doi: 10.1126/science.aaa8765. Epub 2015 Jun 11. PMID: 26068847
  • Li J, Jin X, Liu Y, Li F, Zhang L, Zhu X, Lu Y. “Robust enzyme-silica composites made from enzyme nanocapsules”. Chem Commun (Camb). 2015 Jun 14;51(47):9628-31. doi: 10.1039/c5cc02053k
  • Dejnirattisai, W, Wongwiwat, W, Supasa, S, Jumnainsong, A, Zhang, X., Dai, X., Rouvinsky, A,Jumnainsong, A, Edwards, C, Quyen, NTH, Duangchinda, T, Grimes, JM, Tsai, W-Y, Lai, C-Y, Wang, W-K, Malasit, P, Farrar, J, Simmons, CP, Zhou, ZH, Rey, FA, Mongkolsapaya, J, Screaton, GR (2015) “A new class of highly potent broadly neutralizing antibodies isolated from dengue viremicpatients”. Nature Immunology, 16:170–177. PMCID: PMC4445969
  • Ge, P, Poweleit, NP, Gunsalus, RP, Zhou, ZH (2015) “Deriving de novo atomic models by cryo electron microscopy”. J. Vis. Exp., in press.
  • Jiang, J, Pentelute, BL, Collier, RJ and Zhou, ZH (2015) “Atomic structure of anthrax PA pore elucidates toxin translocation“. Nature. 521:545-549  PMCID: PMC4519040 www.nature.com/doifinder/10.1038/nature14247
  • Clemens, DL, Ge, P, Lee, B-Y, Horwitz, MA and Zhou, ZH (2015) “Atomic structure of a T6SS reveals interlaced array essential to function”. Cell, 160:940-51. doi: 10.1016/j.cell.2015.02.005. PMCID:PMC4351867 
  • Dai, X, Gong, D, Xiao, Y, Wu, T-T, Sun, R, Zhou, ZH (2015) “CryoEM and mutagenesis reveal that the smallest capsid protein cements and stabilizes Kaposi’s sarcoma-associated herpesvirus capsid”.Proc. Natl. Acad. Sci. USA. 112:E649-56. PMCID: PMC4343125.
  • Ge P, Scholl, D, Leiman, PG, Yu, X, Miller, JF and Zhou ZH (2015) “Atomic structures of a bactericidal contractile nanotube in its pre- and postcontraction states”. Nature Struct Mol Biol. 22, 377-82. PMCID: PMC4445970 doi:10.1038/nsmb.2995.
  • Huber RC, Ferreira, AS, Thompson R, Kilbride D, Knutson NS, Devi LS, Toso DB, Zhou ZH, Rubin Y, Schwartz BJ, Tolbert SH (2015) POLARON DYNAMICS. “Long-lived photoinduced polaron formation in conjugated polyelectrolyte-fullerene assemblies”. Science, 348: 1340-1343. Doi:10.1126/science.aaa6850  NIHMSID 978648 
  • Jiang, JS, Chan, H, Cash, DD, Miracco, EJ, Loo, RRO, Upton, HE, Cascio, D, Johnson, RO, Collins, K, Loo, JA, Zhou, ZH, Feigon, J (2015) “Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions”. Science, 350:aab4070, doi:10.1126/science.aab4070. PMCID: PMC4687456
  •  Zhang, X, Ding, K, Yu, X, Chang, W, Sun, J, Zhou, ZH (2015) “In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus”. Nature, 527: 531-534. DOI:10.1038/nature15767. PMID: 26503045. PMCID: PMC5086257
  • Jurado, AR, Huang, CS, Zhang, X, Zhou, ZH, Tong, L (2015) “Structure and substrate selectivity of the 750-kDaα6β6 holoenzyme of geranyl-CoA carboxylase”. Nature Commun, 6:8986, doi:10.1038/ncomms9986. PMCID: PMC4673880. 
  • AhYoung AP, Jiang J, Zhang J, Khoi Dang X, Loo JA, Zhou ZH, Egea PF. (2015) “Conserved SMP domains of the ERMES complex bind phospholipids and mediate tether assembly”. Proc Natl Acad Sci U S A. 112:E3179-88 doi:10.1073/pnas.1422363112. PMCID: PMC448511
  • Volland S, Hughes LC, Kong C, Burgess BL, Linberg KA, Luna G, Zhou ZH, Fisher SK, Williams DS. (2015) “Three-dimensional organization of nascent rod outer segment disk membranes“. Proc Natl Acad Sci U S A. 112(48):14870-5. pii: 201516309. PMCID: PMC4672767.
  • Kaweeteerawat C, Chang CH, Roy KR, Liu R, Li R, Toso D, Fischer H, Ivask A, Ji Z, Zink J, Zhou ZH, Chanfreau GF, Telesca D, Cohen Y, Holden PA, Nel AE, Godwin HA (2015) “Cu Nanoparticles Have Different Impacts in Escherichia coli and Lactobacillus brevis than Their Microsized and Ionic Analogues“. ACS Nano, 9:7215-25. Doi:10.1021/acsnano.5b02021. PMID: 26168153. PMCID: PMC5698005
  • Xu, K, Chan, YP, Bradel-Tretheway, B, Akyol-Ataman, Z, Zhu, Y, Dutta S, Yan L, Feng Y, Wang LF, Skiniotis G, Lee B, Zhou, ZH, Aguilar, HC, Broder, CC and Nikolov, DB (2015) “Crystal structure of the prefusion Nipah virus fusion glycoprotein reveals a novel hexamer-of-trimer assembly”. PLoS Pathogen, 11(12):e1005322. doi: 10.1371/journal.ppat.1005322. PMCID: PMC4672880 
  • Zhou, ZH and Chiou, J (2015) “Protein chainmail variants in dsDNA viruses”. Aims Biophysics, 2(2) 200-218.  doi: 10.3934/biophy.2015.2.200  PMCID: PMC5701804
  • Wang, L.J. and Zhou, Z.H. (2014) “Seeing molecular interactions of large complexes by cryoEM at atomic resolution”. American Laboratory, Jan/Feb issue, 23-25
  • Ge, P. and Zhou, Z.H. (2014) “Chaperone fusion proteins aid entropy-driven maturation of class II viral fusion proteins”, Trends Microbiol, 22:100-106. PMID: 24380727
  • Kui, Y., Wills, E., Lim, H.Y., Zhou, Z.H. and Baines, J. (2014) “Association of herpes simplex virus pUL31 with capsid vertices and components of the capsid vertex specific complex”, J.Virol., 88:3815-25. PMCID: PMC3993549  
  • Gurel, GS, Ge, P, Grintsevich, EE, Shu, R, Blanchoin, L, Zhou, ZH, Reisler, E, Higgs, HN (2014) INF2-mediated severing through actin filament encirclement and disruption. Curr. Biol., 24:156-64. PMCID: PMC3992431
  • Yan, X, Gardone, G, Zhang, X, Zhou, ZH, Baker, TS (2014) “Single particle analysis integrated with microscopy: a high-throughput approach for reconstructing icosahedral particles”. J. Struct. Biol.186:8-18. PMCID: PMC4070310  
  • Zhou, ZH (2014) “Structures of viral membrane proteins by high-resolution cryoEM”. Curr. Opin. Virol., 5C:111-119.
  • Zhou, ZH, Hui, WH, Shah, S, Jih, J, O’Connor, CM, Sherman, MB, Kedes, DH, Schein, S (2014) “Four levels of hierarchical organization including non-covalent chainmail brace the mature tumor herpesvirus capsid against pressurization”, Structure, 22:1385-98 PMCID: in progress.
  • Dai, X. and Zhou, Z.H. (2014) “Purification of herpesvirus virions and capsids”. Bio-protocols, 4(15): e1193. http://www.bio-protocol.org/e1193
  • Dai, X., Gong, D., Wu, T., Sun, R. and Zhou, Z.H. (2014) Organization of capsid-associated tegument components in Kaposi’s sarcoma-associated herpesvirus”. J. Virol., 88: 12694-702. PMCID: PMC4248902
  • Sathiyamoorthy, K, Jiang, J, Hu, Y, Rowe, CL, Möhl, BS, Chen, J, Jiang, W, Mellins, ED, Longnecker, R, Zhou, Z.H. and Jardetzky. TS (2014) “Assembly and architecture of the EBV B cell entry triggering complex”. PLoS Pathogen, 10:e1004309. doi: 10.1371/journal.ppat.1004309. PMCID: PMC4140853
  • Buehler DC1, Marsden MD, Shen S, Toso DB, Wu X, Loo JA, Zhou ZH, Kickhoefer VA, Wender PA, Zack JA, Rome LH. (2014) “Bioengineered vaults: self-assembling protein shell-lipophilic core nanoparticles for drug delivery”. ACS Nano. 8(8):7723-32. (featured on cover). PMCID:PMC4148163
  • Mrazek J, Toso D, Ryazantsev S, Zhang X, Zhou ZH, Fernandez BC, Kickhoefer VA, Rome LH (2014) “Polyribosomes Are Molecular 3D Nanoprinters That Orchestrate the Assembly of Vault Particles”. ACS Nano. 8, 11552-9. PMCID:PMC4245718 (Cover) 
  • Ge P, Durer ZA, Kudryashov D, Zhou ZH, Reisler E. (2014) “Cryo-EM reveals different coronin binding modes for ADP- and ADP-BeFx actin filaments”. Nat Struct Mol Biol. 21:1075-81. PMCID:PMC4388421
  • Chen CC, Zhu C, White ER, Chiu CY, Scott MC, Regan BC, Marks LD, Huang Y, Miao J. “Three-dimensional imaging of dislocations in a nanoparticle at atomic resolution”. Nature. 2013 Apr 4;496(7443):74-7. doi: 10.1038/nature12009. Epub 2013 Mar 27.
  • Huang X, Zhu E, Chen Y, Li Y, Chiu CY, Xu Y, Lin Z, Duan X, Huang Y. “A facile strategy to Pt3Ni nanocrystals with highly porous features as an enhanced oxygen reduction reaction catalyst”. Adv Mater. 2013 Jun 4;25(21):2974-9. Doi: 10.1002/adma.201205315. Epub 2013 Apr 22. PMID: 23606407
  • Zhang, X., Ge, P., Yu, X., Brannan, J.M., Bi, G., Zhang, Q., Schein, S. and Zhou, Z.H. (2013) “Cryo-EM structure of the mature dengue virus at 3.5-Å resolution“. Nature Mol. Struct. Biol., 20: 105-110. PMCID: PMC3593067 (featured on cover)
  • Slaymaker IM, Fu Y, Toso DB, Ranatunga N, Brewster A, Forsburg SL, Zhou ZH, Chen XS. (2013) “Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology”.Nucleic Acids Res. 41: 3446-3456. PMCID: PMC3597688
  • Jiang J, Magilnick N, Tsirulnikov K, Abuladze N, Atanasov I, Ge P, Narla M, Pushkin A*, Zhou ZH*, Kurtz I.* (2013) Single particle electron microscopy analysis of the bovine anion exchanger 1 reveals a flexible linker connecting the cytoplasmic and membrane domains. PLoS One. 8(2):e55408. doi: 10.1371/journal.pone.0055408. PMCID: PMC3564912.  *corresponding authors
  • Jiang, J., Miracco, E.J., Hong, K., Eckert, B., Chan, H., Cash, D.D., Min, B., Zhou, Z.H.*, Collins, K.*, Feigon, J.* (2013) “The architecture of Tetrahymena telomerase holoenzyme”, Nature, 496: 187-192. (highlighted by News and Views, Nature 496, 177-178 and covered by more than 40 popular magazines and reports). PMCID: PMC3817743.  *corresponding authors
  • Yu, X., Jin, L., Jih, J., Shih, C. and Zhou, Z.H. (2013) “3.5Å cryoEM structure of hepatitis B virus core assembled from full-length core protein”, PLoS One, 8(9):e69729. doi: 10.1371/journal.pone.0069729. PMCID: PMC3765168.
  • Dai, X., Yu, X., Gong, H., Jiang, X., Abenes, G., Liu, H., Shivakoti, S., Britt, W.B., Zhu, H., Liu, F. andZhou, Z.H. (2013) “The smallest capsid protein mediates binding of the essential tegument protein pp150 to stabilize DNA-containing capsids in human cytomegalovirus”, PLoS Pathog 9(8): e1003525. doi:10.1371/journal.ppat.1003525. PMCID: PMC3744435
  • Hong K, Upton H, Miracco EJ, Jiang J, Zhou ZH, Feigon J, Collins K (2013) “TetrahymenaTelomerase Holoenzyme Assembly, Activation, and Inhibition by Domains of the p50 Central Hub”. Mol Cell Biol., 33(19):3962-71. PMC3811867
  • Lu, G., Ota, A., Ren, S., Franklin, S., Rau, C.D., Ping, P., Lane, T.F., Zhou, Z.H., Reue, K., Lusis, A.J., Vondriska, T., Wang, Y. (2013). “PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response”. Mol Metab. 2, 405-416.
  • Hui WH, Tang Q, Liu H, Atanasov I, Liu F, Zhu H, Zhou ZH. (2013) “Protein interactions in the murine cytomegalovirus capsid revealed by cryoEM”, Protein Cell, 4, 833-45. doi: 10.1007/s13238-013-3060-7
  • Zhang, X. Guo, H., Jin L., Czornyj E., Hodes, A., Hui, W.H., Nieh, A.W., Miller, J.F. and Zhou, Z.H.(2013) “A new topology of the HK97-like fold revealed in Bordetella bacteriophage by cryoEM at 3.5Å resolution”. eLife, 2:e01299. Doi: 107554/eLife.01299. PMCID: PMC3863775.
  • Weiss NO, Zhou H, Liao L, Liu Y, Jiang S, Huang Y, Duan X. Graphene: an emerging electronic material”. Adv Mater. 2012 Nov 14;24(43):5782-825. doi: 10.1002/adma.201201482. Epub 2012 Aug 29. Review. PMID: 22930422
  • Scott MC, Chen CC, Mecklenburg M, Zhu C, Xu R, Ercius P, Dahmen U, Regan BC, Miao J. “Electron tomography at 2.4-ångström resolution”. Nature. 2012 Mar 21;483(7390):444-7. doi: 10.1038/nature10934.
  • Huang, C.S., Ge., P., Zhou, Z.H. and Tong, L. (2012) “An unanticipated architecture of the 750 kDα6β6 holoenzyme of 3-methylcrotonyl-CoA carboxylase”, Nature, 481, 219-223. PMCID: PMC3271731
  • Hughes, L.C., Ralston, K.S., Hill, K.S., Zhou, Z.H. (2012) “Three-dimensional structure of the trypanosome flagellum suggests that the paraflagellar rod functions as a biomechanical spring”. PLoS One, 7(1):e25700. PMCID: PMC3250385
  • Gopal, A., Zhou, Z.H., Knobler, C.M. and Gelbart, W.M. (2012) “Visualizing large RNA molecules in solution”. RNA, 18(2), 284-299. PMCID: PMC3264915
  • Luo J, Obmolova G, Malia TJ, Wu SJ, Duffy KE, Marion JD, Bell JK, Ge P, Zhou ZH, Teplyakov A, Zhao Y, Lamb RJ, Jordan JL, San Mateo LR, Sweet RW, Gilliland GL. (2012) “Lateral clustering of TLR3:dsRNA signaling units revealed by TLR3ecd:3Fabs quaternary structure”. J. Mol. Biol. 421:112-124. PMID: 22579623
  • Tao, C, Xia, C, Chen, X, Zhou, ZH, Bi, G (2012) “Ultrastructural analysis of neuronal synapses using state-of-the-art nano-imaging techniques”, Neurosci Bull. 28, 321-332.
  • Zhou, Z.H. (2012) “Seeing Engineered Loops in a Gene Delivery Vehicle by cryoEM”. Structure, 8, 1286-1288. PMCID: PMC3422559
  • Xiao Q, Sohn H, Chen Z, Toso D, Mechlenburg M, Zhou ZH, Poirier E, Dailly A, Wang H, Wu Z, Cai M, Lu Y. (2012) “Mesoporous metal and metal alloy particles synthesized by aerosol-assisted confined growth of nanocrystals”. Angew Chem Int Ed Engl. 51:10546-10550. PMID: 23001891
  • Jiang ZK, Koh SB, Sato M, Atanasov IC, Johnson M, Zhou ZH, Deming TJ, Wu L. (2012) “Engineering polypeptide coatings to augment gene transduction and in vivo stability of adenoviruses”.J Control Release.166:75-85. PMID: 23247040.
  • Zhang, X., Guo, H., Jin, L., Miller, J.F., and Zhou, Z.H. (2012) “Atomic structure of Bordetellabacteriophage reveals a jellyroll fold in cement protein and a topologically distinct HK97-like fold in major capsid protein”. Microscopy and Microanalysis 18:72-73. PMC Journal – In progress
  • Xu G, Torres CM, Tang J, Bai J, Song EB, Huang Y, Duan X, Zhang Y, Wang KL. “Edge effect on resistance scaling rules in graphene nanostructures”. Nano Lett. 2011 Mar 9;11(3):1082-6. doi: 10.1021/nl103966t. Epub 2011 Feb 15. PMID: 21322591
  • Liu, H., Wu. L. Zhou, Z.H.* (2011) “Model of the trimeric fiber of human adenovirus 5 and its interactions with the pentameric penton base by cryo-electron microscopy and bioinformatics”. J. Mol. Biol., 406, 764-774. (featured on cover) PMCID: PMC3392045
  • Green, T.J., Rowse, M., Tsao, J., Kang, J., Ge, P., Zhou, Z.H. and Luo, M. (2011) “Access of RNA encapsidated in the nucleocapsid of vesicular stomatitis virus”, J. Virol. 85, 2714-2722. PMCID: PMC3067934
  • Gangalum, RK, Atanasov, IC, Zhou, ZH, Bhat, SP (2011) “aB-crystallin is found in detergent resistant membrane microdomains and is secreted via exosomes from human retinal pigment epithelial cells“.J. Biol. Chem. 286, 3261-3269. PMCID: PMC3030331
  • Yu, X., Shah, S., Lee, M., Dai, W., Lo, P., Britt, W., Zhu, H., Liu, F. and Zhou, Z. H. (2011) “Biochemical and structural characterization of the capsid-bound tegument proteins of human cytomegalovirus“, J. Struct. Biol. 174, 451-460. PMCID: PMC3684277 
  • Zhou, Z. H. (2011) “Atomic resolution cryo electron microscopy of macromolecular complexes”, AdvProtein Chem Struct Biol 82, 1-35. PMCID: PMC3698602
  • Yu, X., Ge, P., Jiang, J., Atanasov, I. and Zhou, Z. H. (2011) “Atomic model of CPV reveals the mechanism used by this single-shelled virus to economically carry out functions conserved inmultishelled reoviruses”, Structure 19, 652-661. PMCID: PMC3405907 (featured on cover)
  • Chen, J., Sun, J., Atanasov, I., Ryazantsev, S. and Zhou, Z. H. (2011) “Electron tomography reveals polyhedrin binding and existence of both empty and full cytoplasmic polyhedrosis virus particles inside infectious polyhedra”, J. Virol. 85, 6077-6081. PMCID: PMC3126316
  •  Meng, H., Yang, S., Li, Z., Xia, T., Chen, J., Ji, Z., Zhang, H., Wang, X., Lin, S., Huang, C., Zhou, Z. H., Zink, J. I. and Nel, A. E. (2011) “Aspect Ratio Determines the Quantity of Mesoporous Silica Nanoparticle Uptake by a Small GTPase-Dependent Macropinocytosis Mechanism”, ACS Nano 5,4434-4447. PMCID: PMC3125420  
  • Ge, P. and Zhou, Z. H. (2011) “Hydrogen-bonding networks and RNA bases revealed by cryo electron microscopy suggest a triggering mechanism for calcium switches”, Proc Natl Acad Sci USA 108, 9637-9642. PMCID: PMC3111329 
  • Buehler, D. C., Toso, D. B., Kickhoefer, V. A., Zhou, Z. H. and Rome, L. H. (2011) “Vaults engineered for hydrophobic drug delivery”, Small. 7, 1432-1439. (featured on cover) PMID: 21506266
  • Yang, Z., Hu, W., Chen, K., Wang, J. Lux, R., Zhou, Z.H. and Shi, W. (2011) “Alanine 32 in PilA is important for PilA stability and type IV pili function in Myxococcus xanthus”. Microbiology, 157, 1920-1928. PMCID: PMC3167889
  • Zhang, X. and Zhou, Z.H. (2011) “Limiting factors in atomic resolution cryo electron microscopy – No simple tricks”. J. Struct. Biol., 175, 253-263.   PMCID: PMC3710782
  • Toso, D.B., Henstra, A.M., Gunsalus, R.P. and Zhou, Z.H. (2011) “Structural, mass, and elemental analyses of storage granules in methanogenic archaeal cells”, Environmental Microbiology, 13, 2587-2599. PMCID: PMC21854518.
  • “Yan, M., Du, J., Gu, Z., Liang, M., Hu, Y., Zhang, W., Priceman, S., Wu, L., Zhou, Z.H., Zheng. L., Segura, T., Tang, Y., Lu, Y. (2010) “A novel intracellular protein delivery platform based on single-protein nanocapsules“. Nature Nanotechnology, 5, 48 – 53. PMID: 19935648
  • Peng, L., Ryazantsev, S., Sun, R. and Zhou, Z. H. (2010) “Three-dimensional visualization of gammaherpesvirus life cycle in host cells by electron tomography“, Structure, 18, 47-58. (cover) PMCID: PMC2866045.
  • Ge P, Tsao, J., Schein, S., Green, T.J., Luo, M., Zhou, Z.H. (2010) “CryoEM model of the bullet-shaped vesicular stomatitis virus“. Science, 327, 689-693. PMCID: PMC2892700
  • Dai, W., Hodes, A., Wong, H. H., Gingery, M., Miller, J. F. and Zhou, Z. H. (2010) “Three-dimensional structure of tropism-switching Bordetella bacteriophage“, Proc Natl Acad Sci U S A 107, 4347-4352. PMCID: PMC2840154
  • Cheng, L., Zhu, J., Hui, W. H., Zhang, X., Honig, B., Fang, Q., Zhou, Z.H. (2010) “Backbone model of an aquareovirus virion by cryo-electron microscopy and bioinformatics“. J. Mol. Biol., 397, 852-863. (featured on cover) PMCID: PMC2900198
  • Zhang, X., M. Boyce, B. Bhattacharya, X. Zhang, S. Schein, P. Roy & Z. H. Zhou (2010) “Bluetongue virus coat protein VP2 contains sialic acid-binding domains, and VP5 resembles enveloped virus fusion proteins“, Proc Natl Acad Sci U S A 107, 6292-6297. PMCID: PMC2852009
  • Zhu, J., Cheng, L., Fang, Q., Zhou, Z.H.* and Honig, B.* (2010) “Building protein models with cryo-electron microscopy density maps based on homology modeling and multi-scale structure refinement“, J. Mol. Biol.  397, 835-851. (featured on cover)  PMCID: PMC2860449  *corresponding authors. 
  • Zhang, X., L. Jin, Q. Fang, W. H. Hui & Z. H. Zhou (2010) 3.3 “A cryo-EM structure of a nonenvelopedvirus reveals a priming mechanism for cell entry“, Cell 141, 472-482.    (featured on cover and CellPaperFlick Video of the issue) PMCID: PMC3412078
  • Faller, M., Toso, D., Matsunaga, M., Atanasov, I., Senturia, R., Chen, Y., Zhou, Z.H.*, Guo, F. * (2010) “DGCR8 recognizes primary transcripts of microRNAs through highly cooperative binding and formation of higher-order structures”. RNA, 16(8):1570-83. PMCID: PMC2905756      *corresponding authors
  • Zhang, X., Zhang, X., Zhou, Z.H. (2010) “Low cost, high Performance hybrid GPU-CPU solution for atomic resolution CryoEM single-particle reconstruction”. J.Struct. Biol., 172, 400-406. PMCID: PMC3382114
  • Huang, C.S., Sadre-Bazzaz, K., Shen, Y., Deng, B., Zhou, Z.H., Tong, L. (2010) “Crystal structure of the a6b6 holoenzyme of propionyl-coenzyme A carboxylase”. Nature, 466, 1001-1005. PMCID: PMC2925307
  • Liu, H., L. Jin, S. B. Koh, I. Atanasov, S. Schein, L. Wu & Z. H. Zhou (2010) “Atomic structure of human adenovirus by cryo-EM reveals interactions among protein networks”, Science 329, 1038-1043.  PMCID: PMC3412078
  • Jin, L., Pan, C., Qi, Z., Zhou, Z.H., Jiang, S. (2010) “Fab crystallization and preliminary X-ray analysis of NC-1, an anti-HIV-1 antibody that recognizes the six-helix bundle core of gp41″. Acta Cryst. F66, 854-857. PMCID: PMC2898479
  • Liu, S., J. He, C. Shih, K. Li, A. Dai, Z. H. Zhou & J. Zhang (2010) “Structural comparisons of hepatitis B core antigen particles with different C-terminal lengths”, Virus Res 149, 241-244. PMID: 20144668
  • Liu, J., Bradley, S.D., Howell, J.K., Zhou, Z.H., Norris, S.J. (2010) “Cellular architecture of Treponema pallidum: the syphilis spirochete“, J. Mol. Biol., 403, 546-561 (Cover) PMCID: PMC2957517
  • Leong, P. A., Yu, X., Zhou, Z. H., and Jensen, G. J. (2010). “Correcting for the ewald sphere in high-resolution single-particle reconstructions.” Methods Enzymol, 482, 369-380. PMCID: PMC3716286
  • Raines KS, Salha S, Sandberg RL, Jiang H, Rodríguez JA, Fahimian BP, Kapteyn HC, Du J, Miao J. “Three-dimensional structure determination from a single view.” Nature. 2010 Jan 14;463(7278):214-7. doi: 10.1038/nature08705. Epub 2009 Dec 16. 
  • Nayak, D. P., Balogun, R. A., Yamada, H., Zhou, Z. H., Barman, S. (2009). “Influenza virus morphogenesis and budding.” Virus Res. (2009), 143(2):147-61.
  • Pan, D., X. Wang, Zhou, Z. H., Chen, W.,  Xu, C., and Lu, Y. (2009) “Synthesis of quaternary semiconductor nanocrystals with tunable band gaps.” Chemistry of Materials, 21, 2489-2493. 
  • Li, F., Ge, P., Hui, W. H., Atanasov, I., Rogers, K., Guo, Q., Osato, D., Falick, A. M., Zhou, Z. H. and Simpson, L. (2009) “Structure of the core editing complex (L-Complex) involved in uridine insertion/deletion RNA editing in trypanosomatid mitochondria“, Proc Natl Acad Sci U S A 106,12306-12310. PMCID: PMC2708173.
  • Guo H, Wang L, Peng L, Zhou ZH, Deng H. (2009) “Open Reading Frame 33 of a gammaherpesvirusencodes a tegument protein essential for virion morphogenesis and egress“. J. Virol., 83, 10582-10595.
  • Song, C., Jiang, H.,  Mancuso, A., Amirbekian, B., Peng, L., Sun, R., Shah, S.S., Zhou, Z.H., Ishikawa, T. and Miao, J. (2008) “Quantitative and high-contrast imaging of single unstained viruses with coherent X-ray“, Phys. Rew. Let. 101, 158101-4