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West/Midwest Consortium

The goal of the West/Midwest Consortium for High-Resolution Cryo Electron Microscopy (cryoEM) is to offer our consortium users free access to an existing core facility at UCLA

Welcome to West/Midwest Consortium (WMC) at EICN, UCLA!

The well-equipped Titan Krios electron microscope, arguably among the best few in the world for the purpose of obtaining atomic resolution models of large complexes, could be used 24 hours a day/7 days a week, as it should be; and by investigators from UCLA and afar in the Western and Midwestern US, and eventually all over the world, as it should be. The establishment of this consortium would make this a reality.

For grant reporting purposes, all publications with data from this consortium-support must contain the following statement at the end of the acknowledgement section:
“The authors acknowledge the use of instruments at the Electron Imaging Center for NanoMachines supported by NIH (1S10RR23057, 1S10OD018111, and 1U24GM116792), NSF (DBI-1338135) and CNSI at UCLA.”

The goal of the West/Midwest Consortium for High-Resolution Cryo Electron Microscopy (cryoEM) is to offer our consortium users free access to an existing core facility at UCLA — the Electron Imaging Center for Nanomachines (EICN). By providing immediate access to direct electron counting and other cutting-edge technologies already established in EICN’s Titan Krios, we strive to promote the field of cryoEM and advance translational research through high-resolution cryoEM structural studies pursued by our consortium users.

We aim to: (1) establish an infrastructure for efficient direct-electron-detection image acquisition, movie preprocessing and data delivery; (2) deliver a streamlined data acquisition pipeline with direct electron detection/counting to facilitate consortium users in their near-atomic and atomic structure determination efforts.

To make reservation, please go to CLMS Titan Krios reservation page